Abstract
PREVIOUS work has described the presence of a specific soluble complement fixing1 and precipitating2 antigen in. some human tumours. This antigen, called G, was first found in the aqueous phase after the extraction of HeLa cells with fluorocarbon1, and since then in other human cell lines of malignant origin3,4. G antigen has not been found in cells of a variety of non-malignant adult and embryonic human tissues2, and with only one exception, in non-malignant4 cell lines. An apparent correlation has recently been shown between the presence of the G antigen and the heterotransplantability to the hamster cheek pouch of several sublines of the KB cell5.
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References
McKenna, J. M., Sanderson, R. P., and Blakemore, W. S., Science, 135, 370 (1962).
McKenna, J. M., Sanderson, R. P., and Blakemore, W. S., Cancer Res., 24, 754 (1964).
McKenna, J. M., and Blakemore, W. S., Nature, 195, 1009 (1962).
McKenna, J. M., Sanderson, R. P., Davis, F. E., and Blakemore, W. S., Cancer Res. (in the press).
McKenna, J. M., Lazarus, H., and Foley, G. E., Exp. Cell Res. (in the press).
McKenna, J. M., and Prier, J. E., Cancer Res. (in the press).
Pope, I. H., and Rowe, W. P., J. Exp. Med., 120, 577 (1964).
Hoggan, M. D., Rowe, W. P., Black, P. H., and R. J. Proc U.S-Nat. Acad. Sci., 53, 12 (1965).
Habel, K., Jensen, F., Pagano, J. L., and Koprowski, H., Proc Soc. Exp. Biol. and Med., 118, 4 (1965).
Habel, K., Virology, 18, 553 (1962).
Habel, K., Virology, 25, 55 (1965).
Roane, P. R., and Roizman, B., Virology, 22, 1 (1964).
Tanaka, S., and Southam, C. M., J. Nat. Cancer Inst., 34, 441 (1965).
Kissling, R. E., and Addison, B. V., J. Nat. Cancer Inst., 32, 981 (1964).
Wyburn-Mason, R., Brit. Med. J., ii, 615 (1957).
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MCKENNA, J., DAVIS, F., PRIER, J. et al. Induction of Neoantigen (G) in Human Amnion (“WISH”) Cells by Herpes Virus A. Nature 212, 1602–1603 (1966). https://doi.org/10.1038/2121602b0
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DOI: https://doi.org/10.1038/2121602b0
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