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Induction of histamine methyltransferase during experimental hydronephrosis: A mechanism of adaptation for histamine homeostasis in rabbit kidney

  • Histamine and Kinins
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Conclusion

The strong raise in histamine content during the first day of experimental hydronephrosis seemed to induce a slow increase of histamine methyltransferase activity, the only histamine metabolizing enzyme in rabbit kidney [4]. This process of adaptation can be interpreted as a defence mechanism against the formation and the release of high amounts of histamine.

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References

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  2. H. Barth, W. Lorenz andI. Niemeyer, Hoppe-Seylers Z. physiol. Chem.354, 1021–1026 (1973).

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Authors and Affiliations

  1. Division of Experimental Surgery and Pathological Biochemistry, Department of Urology and Surgery, University of Marburg, Robert-Koch-Strasse 8, D-355, Marburg a. d. Lahn, Federal Republic of Germany

    H. Barth, K. Naber, K. E. Barthel, I. Niemeyer & W. Lorenz

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  1. H. Barth
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  2. K. Naber
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  3. K. E. Barthel
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  4. I. Niemeyer
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  5. W. Lorenz
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Barth, H., Naber, K., Barthel, K.E. et al. Induction of histamine methyltransferase during experimental hydronephrosis: A mechanism of adaptation for histamine homeostasis in rabbit kidney. Agents and Actions 5, 442–443 (1975). https://doi.org/10.1007/BF01972663

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  • DOI: https://doi.org/10.1007/BF01972663

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