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Role of histamine release in prostaglandin synthesis in anaphylactic shock in guinea-pig

  • Abstract of Papers Given at the ‘5th Annual Meeting of the European Branch of the Histamine Club’, Paris, 6–8 May 1976
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Conclusion

Our conclusion suggests [3,9] that during an anaphylactic shock, in guinea-pigs there are two kinds of prostaglandin synthesis and/or release:

  • - a specific production of PGF2α (bronchoconstrictors) which are released and/or synthetized at the same time as histamine,

  • - a non specific one, the production of PGE and F being secondary to the release of histamine.

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References

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Authors and Affiliations

  1. Départment de Physiologie, Faculté de Médecine Necker-Enfants-Malades, 156 rue de Vaugirard, 75730, Paris

    J. -L. Parrot, F. Dray, G. Allouche, P. Canu, M. -C. Santais & F. Ruff

  2. Unité de Radioimmunologie Analytique, Institut Pasteur, 28, rue du Docteur Roux, 75015, Paris

    J. -L. Parrot, F. Dray, G. Allouche, P. Canu, M. -C. Santais & F. Ruff

Authors
  1. J. -L. Parrot
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  2. F. Dray
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  3. G. Allouche
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  4. P. Canu
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  5. M. -C. Santais
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  6. F. Ruff
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Parrot, J.L., Dray, F., Allouche, G. et al. Role of histamine release in prostaglandin synthesis in anaphylactic shock in guinea-pig. Agents and Actions 7, 117–119 (1977). https://doi.org/10.1007/BF01964904

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  • DOI: https://doi.org/10.1007/BF01964904

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