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Participation of retinal mechanisms in DMT hallucinations

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Zusammenfassung

Intravenöse Injektionen von DMT (1–5 mg/kg) bewirkten neben einer Verkleinerung der visuell evozierten corticalen Potentiale und der lichtinduzierten phasischen Reaktionen retinaler Neurone auch eine starke Verminderung der Spontanaktivität in Einzelfasern des N. opticus. Die Befunde sprechen für eine Beteiligung retinaler Mechanismen beim Zustandekommen optischer Halluzinationen und lassen 5-HT als retinalen Transmitter vermuten.

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Authors and Affiliations

  1. Institut für allgemeine und vergleichende Physiologie der Universität, Schwarzspanierstrasse 17, A-1090, Wien, Austria

    W. -D. Heiss, J. Hoyer & F. Poustka

  2. Neurologische Universitätsklinik, Lazarettgasse 14, A-1090, Wien, Austria

    W. -D. Heiss, J. Hoyer & F. Poustka

Authors
  1. W. -D. Heiss
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  2. J. Hoyer
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  3. F. Poustka
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Supported by the Östereichischen Fonds zur Förderung der wissenschaftlichen Forschung.

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Heiss, W.D., Hoyer, J. & Poustka, F. Participation of retinal mechanisms in DMT hallucinations. Experientia 29, 455–457 (1973). https://doi.org/10.1007/BF01926779

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  • DOI: https://doi.org/10.1007/BF01926779

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