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Occurrence of immunoreactive thyroglobulin in the parafollicular cells of dogs

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Summary

When the canine thyroid gland was stained by immunofluorescence and immunoperoxidase methods using undiluted thyroglobulin antiserum, a considerably stronger immunoreactivity was revealed in the parafollicular cells than in the colloid droplets and follicular cells. After induced hypercalcemia and antithyroid drug treatment, the immunoreactivity of the parafollicular cells coinciding with the movement of secretory granules containing calcitonin was conspicuously decreased. An application of diluted serum (above 1:10) produced a strong reaction in the colloid.

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Authors and Affiliations

  1. Department of Anatomy, Kawasaki Medical School, 701-01, Kurashiki, Okayama, Japan

    Y. Kameda & A. Ikeda

Authors
  1. Y. Kameda
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  2. A. Ikeda
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Additional information

We thank Professor Tsuneo Fujita (Department of Anatomy, Niigata University Medical School) for his critical reading of the manuscript.

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Kameda, Y., Ikeda, A. Occurrence of immunoreactive thyroglobulin in the parafollicular cells of dogs. Experientia 33, 538–540 (1977). https://doi.org/10.1007/BF01922259

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  • DOI: https://doi.org/10.1007/BF01922259

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