Summary
The effects of 4 carbaryl doses (0.375, 0.75, 1.50 and 3 mg/100 g) on the reticuloendothelial system (RES) phagocytic activity were studied 1 h after their administration to male rats. Carbaryl reduced RES phagocytic activity. Results showed a dose-dependent drop in RES phagocytic activity. Carbaryl might act as an inhibitor of phagocytes by saturing them to greater or lesser degree, depending on the dose administered.
Article PDF
Similar content being viewed by others
References
T. M. Saba, Archs intern. Med.126, 1031 (1970).
T. P. Stossel, N. Engl. J. Med.290, 774 (1974).
E. L. Becker et P. M. Henson, Adv. Immun.17, 93 (1973).
D. S. Pearlman, P. A. Ward et E. L. Becker, J. exp. Med.130, 745 (1969).
J. E. Casida, Science146, 1011 (1964).
D. Gaillard, S. Mitjavila et R. Derache, C. r. Acad. Sci. Paris262, 2169 (1966).
D. Schwartz, Méthodes statistiques à l'usage des médecins et des biologistes, 3e ed. Flammarion, Paris 1969.
B. N. Halpern, G. Biozzi, G. Pequignot, B. Delaloye, C. Stiffel et D. Mouton, Path. Biol.7, 1637 (1959).
S. J. Normann, Lab. Invest.31, 161 (1974).
R. J. Feldmann et H. I. Maibach, Toxic. appl. Pharmac.28, 126 (1974).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Pipy, B., Béraud, M. & Gaillard, D. Activité phagocytaire du système réticuloendothélial du rat après administration d'un anticholinestérasique, le carbaryl. Experientia 34, 87–88 (1978). https://doi.org/10.1007/BF01921919
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF01921919