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Les cellules mammotropes et somatotropes de l'antehypophyse chez la souris C3H porteuse de tumeur mammaire spontanée. Etude quantitative au microscope électronique

Mammotropic and somatotropic pituitary cells in spontaneous mammary tumor bearing C3H female mice. A quantitative electron microscope study

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Summary

Pituitaries of mammary tumor-bearing mice (C3H) were examined by quantitative electron microscopy. The results indicate that considerable modifications occur in mammotropic and somatotropic cells. Both types show an increase of the surface of the endoplasmic reticulum and a decrease of the volume of secretory granules (in percent of cytoplasmic volume), suggesting a heightened secretory activity of these cells during mammary carcinogenesis.

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Authors and Affiliations

  1. Laboratoire de cytopathologie et de microscopie électronique, Hôpital Broussais, 96, rue Didot, F-75674, Paris Cédex 14, France

    K. H. Hollmann & J. M. Verley

Authors
  1. K. H. Hollmann
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  2. J. M. Verley
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Additional information

Une partie de ce travail a fait l'objet du mémoire pour le titre d'Assistant étranger de Mlle G. G. Sotiropoulou.

Avec la collaboration technique dévouée de Mme J. Garaudel et l'aide de l'I.N.S.E.R.M., du C.N.R.S. et de la Ligue Nationale Française contre le Cancer.

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Hollmann, K.H., Verley, J.M. Les cellules mammotropes et somatotropes de l'antehypophyse chez la souris C3H porteuse de tumeur mammaire spontanée. Etude quantitative au microscope électronique. Experientia 34, 98–100 (1978). https://doi.org/10.1007/BF01921927

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  • DOI: https://doi.org/10.1007/BF01921927

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