Summary
A new procedure which enables us to observe whole cultured cells autoradiographically by electron microscopy is described. By this method, only a relatively small amount of radioisotope and a relatively short exposure period are needed to get a large enough number of silver grains over the cell. The location of radioactive substances can be examined in relation to internal cell structures, especially the nucleus.
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Katsumoto, T., Takagi, A., Hirano, A. et al. A new device for electron microscope autoradiography of whole cultured cells. Experientia 36, 689 (1980). https://doi.org/10.1007/BF01970142
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DOI: https://doi.org/10.1007/BF01970142