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Effects on prostaglandins F2α, I2, and indomethacin on isolated coronary arteries from healthy and alloxandiabetic dogs

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Summary

Contractile responses of isolated coronary arteries from healthy and alloxan-diabetic dogs to prostaglandin F2α were enhanced by indomethacin and inhibited by prostaglandin I2. The potentiation by indomethacin was more prominent in diabetic vessels than in normal arteries.

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Authors and Affiliations

  1. Research Unit and Semmelweis Medical School, Department of Pharmacodynamics, National Institute of Cardiology, P. O. B. 9-88, H-1450, Budapest, (Hungary)

    I. Palik, P. Hadházy, K. Magyar, B. Malomvölgyi, M. Wagner & G. Pogátsa

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  1. I. Palik
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  2. P. Hadházy
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  3. K. Magyar
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  4. B. Malomvölgyi
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  5. M. Wagner
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  6. G. Pogátsa
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Palik, I., Hadházy, P., Magyar, K. et al. Effects on prostaglandins F2α, I2, and indomethacin on isolated coronary arteries from healthy and alloxandiabetic dogs. Experientia 37, 863–864 (1981). https://doi.org/10.1007/BF01985683

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  • DOI: https://doi.org/10.1007/BF01985683

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