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Erythrocyte deformability improving action of β-pyridylcarbinol tartrate

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Summary

β-Pyridylcarbinol tartrate was found to prevent the hyperosmotically induced worsening of filterability of rat erythrocytes after in vivo treatments. The effect is attributed to the prevention of the morphological change of the erythrocytes from normal discocytes to echinocytes. The study was made using a scanning electron microscope.

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Authors and Affiliations

  1. Department of Pharmacology, Nippon Roche Research Center, Kamakura, (Japan)

    T. Okada, A. Okamoto & K. Nakamura

Authors
  1. T. Okada
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  2. A. Okamoto
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  3. K. Nakamura
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Additional information

Acknowledgment. The authors are grateful to Prof. T. Yanagisawa and Mr I. Uemura for providing them the opportunity to learn about scanning electron microscopy.

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Okada, T., Okamoto, A. & Nakamura, K. Erythrocyte deformability improving action of β-pyridylcarbinol tartrate. Experientia 37, 890–892 (1981). https://doi.org/10.1007/BF01985698

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