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Contraction of the large conductance coronary artery produced by acetylcholine in the mini pig

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  • Pharmacology, Toxicology
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Summary

In the mini pig, acetylcholine reduced the coronary blood flow and constricted the large coronary artery. These effects were abolished by atropine, but not by phentolamine, suggesting that cholinergic mechanisms may be involved in coronary artery vasoconstriction.

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References

  1. Oliva, P. B., Potts, D. E. and Pluss, R. G., New Engl. J. Med.288 (1973) 745.

    Article  CAS  PubMed  Google Scholar 

  2. Dhurandhar, R. W., Watt, D. L., Silver, M. D., Trimble, A. S., and Adelman, A. G., Am. J. Cardiol.30 (1972) 902.

    Article  CAS  PubMed  Google Scholar 

  3. Cheng, T. O., Bashour, T., Kelser, G. A., Weiss, L., and Bacos, J., Circulation47 (1973) 476.

    Article  CAS  PubMed  Google Scholar 

  4. Hart, N. J., Silverman, M. E., and King, S. B., Am. J. Med.56 (1974) 296.

    Article  Google Scholar 

  5. Yasue, H., Touyama, M., Kato, H., Tanaka, S., and Akiyama, F., Am. Heart J.91 (1976) 148.

    Article  CAS  PubMed  Google Scholar 

  6. Yasue, H., Touyama, M., Shimamoto, M., Kato, H., Tanaka, S., and Akiyama, F., Circulation50 (1974) 534.

    Article  CAS  PubMed  Google Scholar 

  7. Sakai, K., J. cardiovasc. Pharmac.3 (1981) 500.

    Article  CAS  Google Scholar 

  8. Fam, W. M. and McGregor, M., Circulation Res.22 (1968) 649.

    Article  CAS  PubMed  Google Scholar 

  9. Takeda, K., Nakagawa, Y., Katano, Y., and Imai, S., Jap. Heart J.18 (1977) 92.

    Article  CAS  PubMed  Google Scholar 

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Nakazawa, M., Takeda, K., Nakagawa, Y. et al. Contraction of the large conductance coronary artery produced by acetylcholine in the mini pig. Experientia 38, 1470–1471 (1982). https://doi.org/10.1007/BF01955776

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  • DOI: https://doi.org/10.1007/BF01955776

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