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Gluconolactonase: a zinc containing metalloprotein

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  • Chimica, Biochimica
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Summary

A metal analysis of bovine hepatic gluconolactonase indicates the presence of at least 1 atom of tightly bound zinc per enzyme subunit in this hexameric protein. Other divalent metals are present in lesser quantities and are subject to removal by EDTA. Activation energies for the manganese and magnesium catalyzed reactions are 5.3 and 11.0 kcal/mole, respectively.

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Authors and Affiliations

  1. Department of Chemistry, Wichita State University, 67208, Wichita, Kansas, USA

    W. R. Carper, Aruna S. Mehra, D. P. Campbell & J. A. Levisky

  2. Frank J. Seiler Research Laboratory, USAF Academy, 80840, Colorado, USA

    W. R. Carper, Aruna S. Mehra, D. P. Campbell & J. A. Levisky

Authors
  1. W. R. Carper
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  2. Aruna S. Mehra
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  3. D. P. Campbell
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  4. J. A. Levisky
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Carper, W.R., Mehra, A.S., Campbell, D.P. et al. Gluconolactonase: a zinc containing metalloprotein. Experientia 38, 1046–1047 (1982). https://doi.org/10.1007/BF01955358

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  • DOI: https://doi.org/10.1007/BF01955358

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