Summary
The ratio between large and small carboxy-terminal forms of cholecystokinin in brain extracts from man, pig, dog, rat, chicken, frog and trout was determined by two sequence-specific radioimmunoassays. It was found that the relative amounts of large forms of cholecystokinin; are higher in mammalian brain than in brains of lower species.
This is a preview of subscription content, log in via an institution to check access.
References
Beinfeld, M.C., Meyer, D.K., Eskay, R.L., Jensen, R.T., and Brownstein, M.J., Brain Res.212 (1981) 51.
Dockray, G.J., Nature264 (1976) 568.
Dockray, G.J., Nature279 (1977) 359.
Dockray, G.J., Gregory, R.A., Hutchinson, J.B., Harris, J.I., and Runswick, M.J., Nature274 (1978) 711.
Dockray, G.J., Experientia35 (1979) 628.
Eng, J., Shiina, Y., Straus, E., and Yalow, R.S., Proc. natl Acad. Sci. USA80 (1983) 638.
Geola, F.L., Hershman, J.M., Warwick, R., Reeve, J.R., Walsh, J.H., and Tourtellotte, W.W., J. clin. Endocr Metab.53 (1981) 278.
Goltermann, N.R., Peptides1 (1982) 101.
Jansen J.B.M.J., and Lamers, C.B.H.W., Life Sci.32 (1983) 911.
Larsson, L.I., and Rehfeld, J.F., Brain Res.165 (1979) 201.
Lorén, I., Alumets, J., Hakanson, R., and Sundler, F., Histochemistry59 (1979) 249.
Rehfeld, J.F., J. biol. Chem.253 (1978) 4022.
Straus, E., Malesci, A., and Yalow, R.S., Proc. natl. Acad. Sci. USA75 (1978) 5711.
Deschenes, R.J., Lorenz, L.J., Haun, R.S., Roos, B.A., Collier, K.J., and Dixon, J.E., Proc. natl Acad. Sci. USA81 (1984) 726.
Jansen, J.B.M.J., and Lamers, C.B.H.W., J. clin. Chem. clin. Biochem.21 (1983) 387.
Jansen, J.B.M.J., and Lamers, C.B.H.W., Clinica chim. Acta131 (1983) 305.
Jansen, J.B.J.M., and Lamers, C.B.H.W., J. immun. Meth.51 (1982) 223.
Gubler, U., Chua, A.O., Hoffman, B.J., Collier, K.J., and Eng, J., Proc. natl Acad. Sci. USA81 (1984) 4307.
Larsson, L.I., and Rehfeld, J.F., Nature269 (1977) 335.
Author information
Authors and Affiliations
Additional information
Supported by the Foundation for Medical Research FUNGO (grant No. 13-37-32). — The authors are indebted to Proff. G. Rosenquist and J.H. Walsh for their generous gift of antibody 5135 and to Proff. V. Mutt and N. Yanaihara for their generous gifts of several CCK-preparations.
Rights and permissions
About this article
Cite this article
Jansen, J.B.M.J., Lamers, C.B.H.W. Ratio between large and small carboxy-terminal molecular forms of cholecystokinin in brains of different species. Experientia 42, 1240–1241 (1986). https://doi.org/10.1007/BF01946403
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF01946403