Summary
Interleukin-1 (II-1) was added to collagen lattice cultures of human skin fibroblasts. No cell division was induced, the ability of fibroblasts to contract the lattices was decreased and a dose-related inhibition of collagen synthesis without effect on non-collagen proteins was found. Indomethacin had no influence on these effects.
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Gillery, P., Coustry, F., Pujol, J.P. et al. Inhibition of collagen synthesis by interleukin-1 in three-dimensional collagen lattice cultures of fibroblasts. Experientia 45, 98–101 (1989). https://doi.org/10.1007/BF01990461
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DOI: https://doi.org/10.1007/BF01990461