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Dopamine-induced relaxation in human pulmonary arteries

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Summary

Dose-dependent relaxations were induced by dopamine in human pulmonary arteries that had been contracted with prostaglandin F2α without α-adrenergic blocking agents. The dopamine-induced relaxation was inhibited by haloperidol and fluphenazine, but not by domperidone, suggesting that this relaxation was mediated via DA1 receptors.

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Authors and Affiliations

  1. Department of Pharmacology, Shimane Medical University, Izumo, 693, Shimane, Japan

    Y. Kobayashi & K. Hattori

  2. Department 1st Surgery, Shimane Medical University, Izumo, 693, Shimane, Japan

    M. Yamauchi, K. Yamada & A. Nakase

Authors
  1. M. Yamauchi
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  2. Y. Kobayashi
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  3. K. Hattori
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  4. K. Yamada
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  5. A. Nakase
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Yamauchi, M., Kobayashi, Y., Hattori, K. et al. Dopamine-induced relaxation in human pulmonary arteries. Experientia 45, 150–152 (1989). https://doi.org/10.1007/BF01954854

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  • DOI: https://doi.org/10.1007/BF01954854

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