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Evaluation of tricalciumphosphate/ hydroxyapatite cement for tooth replacement: an experimental animal study

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Abstract

A calciumphosphate cement, consisting mainly of tricalciumphosphate (85% α-TCP and 15% β-TCP), was inserted in 16 surgical defects created in the tibia of goats. X-ray diffraction (XRD) and energy dispersive spectroscopy (EDS) showed that after 3 months of implantation the α-TCP was transformed to hydroxyapatite (HA). Histological evaluation revealed that the presence of cement stimulated the ingrowth of bone compared with unfilled cavities. Active resorption and remodelling of cement particles was observed. The cement did not evoke an inflammatory reaction. At 6 months after implantation no further changes in the composition of the cement occurred. All remaining material was surrounded by mature bone.

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Authors and Affiliations

  1. Department of Oral Function, Laboratory of Biomaterials, Dental School, University of Nijmegen, PO Box 9101, 6500 HB, Nijmegen, The Netherlands

    J. A. Jansen, J. E. De Ruijter, H. G. Schaeken & J. P. C. M. Van Der Waerden

  2. Department de Ciència dels Materials i Enginyeria Metal-lúrgica, Universitat Politècnica de Catalunya, Avda.Diagonal, 647, 08028, Barcelona, Spain

    J. A. Planell & F. C. M. Driessens

Authors
  1. J. A. Jansen
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  2. J. E. De Ruijter
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  3. H. G. Schaeken
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  4. J. P. C. M. Van Der Waerden
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  5. J. A. Planell
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  6. F. C. M. Driessens
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Jansen, J.A., De Ruijter, J.E., Schaeken, H.G. et al. Evaluation of tricalciumphosphate/ hydroxyapatite cement for tooth replacement: an experimental animal study. J Mater Sci: Mater Med 6, 653–657 (1995). https://doi.org/10.1007/BF00123447

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  • DOI: https://doi.org/10.1007/BF00123447

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