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Reaction of 2-methylene-3-oxoquinuclidine with phenol and naphthols

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

C-Alkylation in the ortho position of phenol and naphthols occurs in the reaction of 2-methylene-3-oxoquinuclidine with sodium phenoxide and sodium derivatives of naphthols. The structures of the products were confirmed by IR, PMR, and mass spectroscopic data.

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Literature cited

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Authors and Affiliations

  1. S. Ordzhonikidze All-Union Scientific-Research Pharmaceutical-Chemistry Institute, 119021, Moscow

    V. Ya. Vorob'eva, K. F. Turchin, E. E. Mikhlina, V. A. Bondarenko, A. I. Ermakov, Yu. N. Sheinker & L. N. Yakhontov

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  1. V. Ya. Vorob'eva
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  2. K. F. Turchin
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  3. E. E. Mikhlina
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  4. V. A. Bondarenko
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  5. A. I. Ermakov
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  6. Yu. N. Sheinker
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  7. L. N. Yakhontov
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Vorob'eva, V.Y., Turchin, K.F., Mikhlina, E.E. et al. Reaction of 2-methylene-3-oxoquinuclidine with phenol and naphthols. Chem Heterocycl Compd 13, 1104–1109 (1977). https://doi.org/10.1007/BF00480147

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  • DOI: https://doi.org/10.1007/BF00480147

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