Conclusions
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1.
A linear analog of luliberin is a luliberin antagonist, whereas a cyclic analog is a superagonist of it.
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2.
Pharmacological tests of the cyclic luliberin analog and its linear precursor confirmed the hypothesis of a quasicyclic structure of the biologically active conformation of luliberin.
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Translated from Problemy Éndokrinologii, Vol. 31, No. 4, pp. 52–55, July–August, 1985.
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Korkhov, V.V., Makusheva, V.P., Lupanova, G.E. et al. Investigation of the influence of a cyclic luliberin analog on ovulation. Neurosci Behav Physiol 16, 516–519 (1986). https://doi.org/10.1007/BF01191458
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DOI: https://doi.org/10.1007/BF01191458