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Synthesis and stereochemistry of phenylethynylated 1-(2-ethoxyethyl)-3-methylpiperidin-4-ones. XIX

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Summary

The synthesis of 1-(2-ethoxyethyl)-3-methylpiperidine-4-one is described. The stereochemistry of phenylethynylation of this compound has been studied. The configuration of stereoisomeric phenylethynyl alcohols has been determined by NMR13C- and IR spectra.

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Authors and Affiliations

  1. Institute of Chemical Sciences, Academy of Sciences of the Kazakh SSR, Alma-Ata

    K. D. Praliev, V. K. Yu, D. V. Sokolov & E. I. Khokhlova

Authors
  1. K. D. Praliev
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  2. V. K. Yu
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  3. D. V. Sokolov
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  4. E. I. Khokhlova
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Additional information

Translated from Khimiko-farmatsevticheskii Zhurnal, Vol. 20, No. 6, pp. 679–683, June, 1986.

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Praliev, K.D., Yu, V.K., Sokolov, D.V. et al. Synthesis and stereochemistry of phenylethynylated 1-(2-ethoxyethyl)-3-methylpiperidin-4-ones. XIX. Pharm Chem J 20, 393–397 (1986). https://doi.org/10.1007/BF00758332

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  • DOI: https://doi.org/10.1007/BF00758332

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