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Degradation of 4-hydroxyphenylacetate by Xanthobacter 124X

Physiological resemblance with other Gram-negative bacteria

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Abstract

Xanthobacter 124X when grom on 4-hydroxyphenylacetate was able to hydroxylate this compound yielding homogenisate. Ring fission of this latter compound gave maleylacetoacetate which was isomerized to fumarylacetoacetate. The isomerase involved resembled maleylacetoacetate isomerases in Gram-negative bacteria in that glutathione was required for activity. Fumarate and acetoacetate were both detected as products of the hydrolysis of fumarylacetoacetate.

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Authors and Affiliations

  1. Department of Microbiology, Agricultural University, H. van Suchtelenweg 4, 6703 CT, Wageningen, The Netherlands

    W. J. J. Van Den Tweel, R. J. J. Janssens & J. A. M. De Bont

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  1. W. J. J. Van Den Tweel
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  2. R. J. J. Janssens
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  3. J. A. M. De Bont
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Van Den Tweel, W.J.J., Janssens, R.J.J. & De Bont, J.A.M. Degradation of 4-hydroxyphenylacetate by Xanthobacter 124X. Antonie van Leeuwenhoek 52, 309–318 (1986). https://doi.org/10.1007/BF00428642

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