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Investigation of fluid flow patterns in a hollow fiber module using magnetic resonance velocity imaging

  • Boreactor and Reactor Performance
  • Published:
Biotechnology Techniques

Summary

Magnetic Resonance Imaging (MRI) was used to obtain new information about fluid flow patterns in hollow fiber reactors. Significant changes in inlet flow distribution were observed as a function of Reynolds number. Images taken at the tube bundle entrance and exit showed that maldistribution of flow persists throughout the module. Furthermore, the results suggest that individual fibers act in a mixed degree as feeders or collectors depending upon radial position. These effects must be considered when modelling or designing hollow fiber reactors.

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References

  • Dixon, R.L. and Ekstrand, K.E. (1982).Med. Phys. 9(6), 807–818

    Google Scholar 

  • Park, J.K. and Chang, H.N. (1986).AIChE J. 32(12), 1937–1947

    Google Scholar 

  • Saloner, D. and Moran, P.R. (1987).Med. Phys. 14(2), 167–171

    Google Scholar 

  • Singer, J.R. (1978).J. Phys. E. 11, 281–291

    Google Scholar 

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Authors and Affiliations

  1. Department of Chemical Engineering, Worcester Polytechnic Institute, 01609, Worcester, MA, USA

    B. J. Pangrle & D. DiBiasio

  2. Department of Biomedical Engineering, Worcester Polytechnic Institute, 01609, Worcester, MA, USA

    E. G. Walsh & S. Moore

Authors
  1. B. J. Pangrle
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  2. E. G. Walsh
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  3. S. Moore
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  4. D. DiBiasio
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Pangrle, B.J., Walsh, E.G., Moore, S. et al. Investigation of fluid flow patterns in a hollow fiber module using magnetic resonance velocity imaging. Biotechnol Tech 3, 67–72 (1989). https://doi.org/10.1007/BF01876224

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  • DOI: https://doi.org/10.1007/BF01876224

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