Skip to main content
SpringerLink
Log in

Microencapsulation with poly(vinyl amine) and alginate

  • Published:
Biotechnology Techniques

Summary

Poly(vinyl amine) and alginate were used as the materials for microencapsulation. IW32 (a murine erythroleukemia cell line) cells were cultured within the capsules to a density of 8×107 cells/ml, 40 times that obtained in the free-cell culture. Erythropoietin accumulated in the microcapsule to a concentration of 7.0 U/ml, about three times that in the extra-capsular medium and 14 times the concentration found in the medium of free-cell culture.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Bano, M. C., Cohen, S., Visscher, K. B., Allcock, H. R., and Langer, R. (1991). Biotechnology, 9, 468–471.

    Article  CAS  Google Scholar 

  • Bayer, E., Geckeier, K. and Weingartner, K. (1980). Makromol. Chem., 181, 585–593.

    Article  CAS  Google Scholar 

  • Chang, T.M.S. (1987). Biomat., Art. Cells Art. Org., 15, 1–20.

    Google Scholar 

  • Crooks, C. A., Douglas, J. A., Broughton, R. L. and Sefton, M. V. (1990). J. of Biomed. Mater. Res., 24, 1241–1262.

    Article  CAS  Google Scholar 

  • Krystal, G. (1983). Exp. Hematol. 11, 649–652

    CAS  Google Scholar 

  • Lim, F., (1985). “Biomedical Applications of Microencapsulation”, CRC Press, Inc.

  • Sawyer, S. T., Krantz, S. B., and Goldwasser, E. (1987). J. Biol. Chem., 262, 5554–5562.

    CAS  Google Scholar 

  • Sun, A.M., and O'shea, G.M. (1985). J. Control. Release, 2, 137–141.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute of Biochemistry, Institute of Biomedical Engineering, National Yang Ming Medical College, Taipei, Taiwan, R.O.C.

    F. F. Wang, C. R. Wu & Y. J. Wang

  2. Institute of Botany, Academia Sinica, Nankang, Taipei, Taiwan, R.O.C.

    J. F. Shaw

Authors
  1. F. F. Wang
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. F. Shaw
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. C. R. Wu
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Y. J. Wang
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Wang, F.F., Shaw, J.F., Wu, C.R. et al. Microencapsulation with poly(vinyl amine) and alginate. Biotechnol Tech 6, 185–188 (1992). https://doi.org/10.1007/BF02438830

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02438830

Keywords

Search

Navigation