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Atypical metabolisms and biochemical cycles imposing the cancerous state on plant cells

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Abstract

The biological, morphological and biochemical characteristics which define plant cancer cells at the end of a neoplasic progression in the absence of pathogens and which distinguish them from tumorous cells are summarized. Such plant cancer cells have in common with animal cancer cells many metabolic disturbances. The present paper reviews the biochemical changes in nitrogen, carbon, sugar and heme metabolisms which contribute to polyamine (PAs) accumulation. It indicates how these changes are interconnected and even form between each other biochemical cycles which likely maintain these cells in their irreversible state. The role of these cycles in the maintenance of such cells under a probable permanent oxidative stress is debated.

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Authors and Affiliations

  1. Hormonologie végétale, Institut de Botanique B 22, Univ. de Liége, Sart Tilman, B-4000, Liége, Belgium

    Th. Gaspar, B. Bisbis & C. Kevers

  2. Physiologie et Biochimie végétales, Univ., CH-1211, Genève 4, Switzerland

    Th. Gaspar, C. Penel & H. Greppin

  3. Physiologie et Biochimie végétales, Univ., F-14032, Caen, France

    F. Le Dily, J.P. Billard & C. Huault

  4. Biologie cellulaire, Fac. de Pharmacie, Univ. de Tours, 31, av., F-37200, Tours, France

    F. Garnier & M. Rideau

  5. Biologie générale, Univ., B-4000, Liège, Belgium

    J.M. Foidart

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  1. Th. Gaspar
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Gaspar, T., Bisbis, B., Kevers, C. et al. Atypical metabolisms and biochemical cycles imposing the cancerous state on plant cells. Plant Growth Regulation 24, 135–144 (1998). https://doi.org/10.1023/A:1005972924568

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