Skip to main content
SpringerLink
Log in

Trace elements in skin epitheliomas

  • Published:
Journal of Radioanalytical and Nuclear Chemistry Aims and scope Submit manuscript

Abstract

Skin tissue samples from 41 patients suffering from skin epitheliomas were analyzed by the PIXE method. Skin samples from the non-affected areas and blood serum were also analyzed for the same patients. The elements determined were K, Ca, Cr, Mn, Fe, Ni, Cu, Zn, Br, Rb, and Pb. Their concentrations in the healthy skin and the serum were normal. The concentrations in the lesions were nearly the same for both basal cell and squamus cell epitheliomas (BCE and SCC) except for higher zinc and lower bromine values in the BCE samples. However, substantial differences were observed between the affected and non-affected skin.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. I. H. TIPTON, M. J. COOK, R. L. STEINER, C. A. BOYE, H. M. PERRY JR., H. A. SCHROEDER, Health Phys., 9 (1963) 89.

    PubMed  Google Scholar 

  2. I. H. TIPTON, M. J. COOK, Health Phys., 9 (1963) 103.

    PubMed  Google Scholar 

  3. Elemental Analysis of Biological Materials, Techn. Report Ser. 197, IAEA, Vienna, 1980.

  4. G. V. IYENGAR, W. E. KOLLMER, H. J. M. BOWEN, The Elemental Composition of Human Tissues and Body Fluids, Verlag Chemie-Weinheim, New York, 1978.

    Google Scholar 

  5. S. D. SOMAN, K. T. JOSEPH, S. J. RAUT, C. D. MULAY, M. PARAMESHWARAN, V. K. PANDAY, Health Phys., 19 (1970) 641.

    PubMed  Google Scholar 

  6. E. I. HAMILTON, M. J. MINSKI, J. J. CLEARY, Sci. Total Environ., 1 (1972) 341.

    Google Scholar 

  7. G. F. CLEMENTE, L. GIGNA ROSSI, G. P. SANTARONI, J. Radioanal. Chem., 37 (1977) 549.

    Google Scholar 

  8. A. A. KATSANOS, Proc. Intern. Symp. on Nuclear Activation Technique in Life Sciences, Vienna, 22–26 May 1978, paper No 103.

  9. L. S. HURLEY, Fed. Proc., 35 (1976) 2271.

    PubMed  Google Scholar 

  10. J. F. RIORDAN, Med. Clin. North Amer., 60 (1976) 871.

    Google Scholar 

  11. B. L. O'DELL, Med. Clin. North Amer., 60 (1976) 907.

    Google Scholar 

  12. R. I. HENKIN, Med. Clin. North Amer., 60 (1976) 1023.

    Google Scholar 

  13. W. MERTZ, Science, 213 (1981) 1332.

    PubMed  Google Scholar 

  14. B. PAPASSOTIRIOU, Trace Elements Concentration Study in Skin Tumors, Ph. D. Thesis, Athens, 1984 (in Greek).

  15. A. MOLOKHIS, B. PORTNOY, A. DYER, Brit. J. Derm., 101 (1979) 567.

    PubMed  Google Scholar 

  16. K. G. MALMQVIST, L. E. CARLSSON, B. FORSLIND, G. M. ROOMANS, K. R. AKSELSSON, Nucl. Instr. Meth., B3 (1984) 611.

    Google Scholar 

  17. J. A. KAPETANAKIS, Dermatology, Parissianos G. K., Athens, 1969 (in Greek).

  18. A. KATSANOS, A. XENOULIS, A. HADJIANTONIOU, R. W. FINK, Nucl. Instr. Methods, 137 (1976) 119.

    Google Scholar 

  19. A. A. KATSANOS, Elemental X-ray Microanalysis by Charged Particle Excitation with Application to Local Problems, Report IAEA Contract No. 1608/RB, 1975.

  20. S. A. E. JOHANSSON, T. B. JOHANSSON, Nucl. Instr. Methods, 137 (1976) 473.

    Google Scholar 

  21. W. HUDA, D. K. BEWLEY, Phys. Meth. Biol., 24 (1979) 711.

    Google Scholar 

  22. R. L. WALTER, R. D. WILLIS, W. F. GUTKNECHT, R. W. SHAW, Nucl. Instr. Methods, 142 (1977) 181.

    Google Scholar 

  23. A. A. KATSANOS, Trace Elements Analysis, IAEA Report No. 1488, 1979.

  24. R. L. WATSON, J. A. DEMAREST, A. LANGEBERG, F. E. JENSON, J. R. WHITE, C. C. BAHR, IEEE Trans. Nucl. Sci., 26 (1979) 1352.

    Google Scholar 

  25. V. VALCOVIC, Nucl. Instr. Methods, 142 (1977) 151.

    Google Scholar 

  26. J. L. CAMBELL, IEEE Trans. Nucl. Sci., 26 (1979) 1363.

    Google Scholar 

  27. I. HASSELMANN, W. KOENIG, F. W. RICHTER, U. STEINER, U. WATJEN, J. C. BODE, W. OHTA, Nucl. Instr. Methods, 142 (1977) 163.

    Google Scholar 

  28. J. L. CAMBELL, S. B. RUSSEL, S. FAIG, C. W. SCHULTE, R. W. OLLERHEAD, R. R. GINGERICH, Nucl. Instr. Methods, 181 (1981) 285.

    Google Scholar 

  29. T. A. CAHILL, Ann. Rev. Nucl. Part. Sci., 30 (1980) 211.

    Google Scholar 

  30. A. KATSANOS, A. HADJIANTONIOU, Nucl. Instr. Methods, 149 (1978) 469.

    Google Scholar 

  31. A. H. KHAN, M. KHALIQUZZAMAN, M. B. ZAMAN, M. HUSAIN, M. ABDULLAH, S. AKHTER, J. Radioanal. Chem., 57 (1980) 157.

    Google Scholar 

  32. P. K. KAKANIS, A. A. KATSANOS, Nucl. Instr. Methods, B3 (1984) 311.

    Google Scholar 

  33. G. DECONNICK, F. BODART, E. DEMOULIN, Nucl. Instr. Methods, 181 (1981) 259.

    Google Scholar 

  34. I. STRATIGOS, Contribution to the Study of Carcinogenic Effect of the Solar Radiation in Skin, Ph. D. Thesis, Athens, 1968 (in Greek).

  35. I. J. T. DAVIES, M. MUSA, T. L. DORMANDY, J. Clin. Path., 21 (1968) 359.

    PubMed  Google Scholar 

  36. L. MING-CHIEN, T. MING-GUANG, C. JUN-FA, S. KANG-lONG, C. ZHI-XIANG, C. JIA-HUA, Z. WEN, L. WEI-LI, X. ZONG-GIN, K. AN-KUN, Nucl. Instr. Methods, 181 (1981) 309.

    Google Scholar 

  37. M. BERTI, G. BUSO, P. COLAUTTI, G. MOSCHINI, B. M. STIEVANO, C. TREGNAGHI, Anal. Chem., 49 (1973) 1313.

    Google Scholar 

  38. A. A. KATSANOS, A. HADJIANTONIOU, N. PANAYIOTAKIS, M. TZOUMEZI, Health Related Monitoring of Trace Elements by PIXE, IAEA-TECDOC 330, 1985, p. 67.

  39. T. PARADELLIS, N. PANAYIOTAKIS, J. Radioanal. Chem., 59 (1980) 221.

    Google Scholar 

  40. I. L. MULAY, R. ROY, B. E. KNOX, N. H. SUHR, W. E. DELANEY, J. Nat. Cancer Inst., 47 (1971) 1.

    PubMed  Google Scholar 

  41. A. DANIELSEN, E. STEINNES, J. Nucl. Med., 11 (1970) 260.

    PubMed  Google Scholar 

  42. M. J. RENAN, C. E. ALBRECHT, D. T. L. JONES, Nucl. Instr. Methods, 181 (1981) 297.

    Google Scholar 

  43. H. A. VAN RINSVLT, R. D. LEAR, W. R. ADAMS, Nucl. Instr. Methods, 142 (1977) 171.

    Google Scholar 

  44. R. O. ALLEN, E. STEINNES, M. D. BAKER, IAEA-SM-227/57, 1978, p. 447.

  45. K. GRIFFITH, E. B. WRIGHT, T. L. DORMANDY, Nature, 241 (1973) 60.

    Google Scholar 

  46. A. MARUHASHI, K. KOBAYASHI, K. SHIMA, T. ISHIHARA, T. KUSUMOTO, T. INADA, M. AKISADA, Nucl. Instr. Meth. Phys. Res., B3 (1984) 382.

    Google Scholar 

  47. J. H. BLOCK, E. B. ROCHE, T. O. SOIN, C. O. WILSON, Inorganic Medicinal and Pharmaceutical Chemistry, Lea and Febiger, Philadelphia, 1974.

    Google Scholar 

  48. C. J. FLICKINGER, J. C. BROWN, H. C. KUTCHAI, J. W. OGILVIE, Medical Cell Biology, Holt Saunders International Editions, 1979.

  49. M. SHVAPIL, J. N. RYAN, C. F. ZUKOFSKI, Proc. Soc. Exper. Biol. Med., 140 (1972) 642.

    Google Scholar 

  50. M. SHVAPIL, Life Sci., 13 (1973) 1041.

    PubMed  Google Scholar 

  51. M. SHVAPIL, Med. Clin. North. Amer., 60 (1976) 1047.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. “A. SYGROS” Hospital, Athens, Greece)

    V. Papassotiriou, S. Georgala & J. Stratigos

  2. Nuclear Research Center “DEMOCRITOS”, GR 15310, Aghia Paraskevi, Greece)

    N. Panayotakis, A. Hadjiantoniou & A. A. Katsanos

Authors
  1. V. Papassotiriou
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. S. Georgala
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. J. Stratigos
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. N. Panayotakis
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. A. Hadjiantoniou
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. A. A. Katsanos
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Supported in part by the Hellenic Anticancer Society.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Papassotiriou, V., Georgala, S., Stratigos, J. et al. Trace elements in skin epitheliomas. Journal of Radioanalytical and Nuclear Chemistry, Articles 109, 89–100 (1987). https://doi.org/10.1007/BF02117526

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02117526

Keywords

Search

Navigation