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Tumor-Associated Antigen Peptides as Anti-Metastatic Vaccines

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Abstract

Cytotoxic T-lymphocytes (CTLs) kill abnormal cells. CTLs recognize major histocompatibility complex class I molecules in complex with peptides derived from relevant antigens. The identification of tumor associated antigen peptides enabled the design of anti-tumor and anti-metastatic vaccines in a murine lung carcinoma.

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Authors and Affiliations

  1. Department of Immunology, The Weizmann Institute of Science, Rehovot, 76100, Israel

    Lea Eisenbach, Ofer Mandelboim, Erez Bar-Haim, Lior Carmon, Hernan Copcow, Khaled El-Shami, Adrian Paz, Dan Popovic, Ezra Vadai, Esther Tzehoval & Michael Feldman

  2. Department of Organic Chemistry, The Weizmann Institute of Science, Rehovot, 76100, Israel

    Mati Fridkin

Authors
  1. Lea Eisenbach
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  2. Ofer Mandelboim
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  3. Erez Bar-Haim
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  4. Lior Carmon
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  5. Hernan Copcow
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  6. Khaled El-Shami
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  7. Adrian Paz
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  8. Dan Popovic
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  9. Ezra Vadai
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  10. Esther Tzehoval
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  11. Michael Feldman
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  12. Mati Fridkin
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Eisenbach, L., Mandelboim, O., Bar-Haim, E. et al. Tumor-Associated Antigen Peptides as Anti-Metastatic Vaccines. Letters in Peptide Science 5, 323–328 (1998). https://doi.org/10.1023/A:1008874820160

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