Abstract
Twenty-six different species of keratinophilic fungi were examined to determine their ability to utilize free cystine. Of the fungi tested, the majority metabolized free L-cystine in a glucose-peptone culture medium. Cystine was used as source of sulfur, and carbon and nitrogen as well. Excess sulfur was excreted into the culture fluid, as thiosulfate and sulfate, following oxidation. The rate of cystine oxidation varied with the different fungal strains, but was maximal for Graphium penicilloideus (88.5%). Low quantities of thiols were found in the medium. Cystine oxidation and inorganic thiosulfate excretion were found to correlate significantly (r = 0.94).
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Malviya, H.K., Hasija, S.K. & Rajak, R.C. In vitro utilization of L-cystine by keratinophilic fungi inhabiting a gelatin factory. Mycopathologia 118, 147–152 (1992). https://doi.org/10.1007/BF00437147
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DOI: https://doi.org/10.1007/BF00437147