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Magnetic particles in the lung: A probe for alveolar macrophage function

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Il Nuovo Cimento D

Summary

Ferrimagnetic particles instilled intratracheally into the lungs are phagocytized by alveolar macrophages. After these particles are magnetized by an external field, they produce a remanent field which decays rapidly due to particle misalignment from cytoplasmic motion (relaxation). Changes in relaxation rate with time following instillation might be related to cytoplasmic motility.

Riassunto

Particelle ferromagnetiche immesse per via intratracheale nei polmoni sono fagocitate da macrofagi alveolari. Dopo che queste particelle sono state magnetizzate dal campo esterno, esse producono un campo residuo che decade rapidamente a causa del disallineamento delle particelle dovuto al movimento citoplasmatico (rilassamento). I cambiamenti nel valore di rilassamento nel tempo successivo all’immissione potrebbero essere connessi alla mobilità citoplasmatica.

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Author notes

  1. P. Gehr

    Present address: Anatomisches Institut, Universität Bern, Postfach 139, CH-3000, Berne 9, Switzerland

  2. I. Nemoto

    Present address: College of Science and Engineering, Tokyo Denki University, 350-03, Hatoyama-mura, Saitama-Ken, Japan

Authors and Affiliations

  1. Harvard School of Public Health, 02115, Boston, Mass

    P. Gehr, J. D. Brain, I. Nemoto & S. B. Bloom

Authors
  1. P. Gehr
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  2. J. D. Brain
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  3. I. Nemoto
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  4. S. B. Bloom
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Gehr, P., Brain, J.D., Nemoto, I. et al. Magnetic particles in the lung: A probe for alveolar macrophage function. Il Nuovo Cimento D 2, 617–623 (1983). https://doi.org/10.1007/BF02455959

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  • DOI: https://doi.org/10.1007/BF02455959

PACS. 87.40

PACS. 85.25

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