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Effects of diuretics on the intensity of lipid peroxidation and antioxidant protection of blood plasma

  • Biophysics and Biochemistry
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

An increase in the content of primary and final lipid peroxidation (LPO) products and a decrease in the fat- and water-soluble antioxidants in blood plasma are revealed in a study of hypohydration induced by administration of 40 mg furosemide alone or in combination with 1 tablet of triampure. Intensification of free radical processes in states simulating weightlessness may be related to the loss of fluid due to transformation of water-electrolyte metabolism.

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Authors and Affiliations

  1. Institute of Medico-Biological Problems, Ministry of Public Health, Institute of Experimental Cardiology, Russian Academy of Medical Sciences, Moscow

    O. E. Lan'shina, A. V. Lebedev, V. Yu. Luk'yanyuk & V. A. Loginov

Authors
  1. O. E. Lan'shina
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  2. A. V. Lebedev
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  3. V. Yu. Luk'yanyuk
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  4. V. A. Loginov
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Additional information

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 117, No 5, pp. 478–479, May, 1994

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Lan'shina, O.E., Lebedev, A.V., Luk'yanyuk, V.Y. et al. Effects of diuretics on the intensity of lipid peroxidation and antioxidant protection of blood plasma. Bull Exp Biol Med 117, 474–475 (1994). https://doi.org/10.1007/BF02444291

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  • DOI: https://doi.org/10.1007/BF02444291

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