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Changes in the coronary vessel tone resulting from immobilization stressA

  • Pathological Physiology and General Pathology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Coronary perfusion pressure at increasing flow of Krebs-Henseleit buffer in the hearts of animals exposed to stress is decreased 23%, a decrease which is eliminated by administering the NO-synthase blocker NG-monomethyl-L-arginine. Stimulated vasodilation of coronary vessels (administration of sodium nitroprusside and acetylcholine) decreases markedly in stressed animals; the concentrations of sodium nitroprusside and acetylcholine inducing a half-maximum coronary response increase.

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Authors and Affiliations

  1. Chair of Normal Physiology, Medical Institute, Vitebsk

    P. Solodkov & A. P. Bozhko

Authors
  1. P. Solodkov
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  2. A. P. Bozhko
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 118, No 9, pp. 246–249, September, 1994

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Solodkov, P., Bozhko, A.P. Changes in the coronary vessel tone resulting from immobilization stressA. Bull Exp Biol Med 118, 943–946 (1994). https://doi.org/10.1007/BF02445779

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  • DOI: https://doi.org/10.1007/BF02445779

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