Abstract
A morphometric analysis of mast cell populations in the subcutaneous tissue and mesentery from rats demonstrated stimulation of heparin secretion by adrenocorticotropic hormone. Thirty minutes after the administration of this hormone to unstressed rats, the functional stutus of mast cells did not differ from that of such cells from rats stressed by being immobilized for 30 min after receiving physiological saline instead of the hormone. In contrast, the 30-minute immobilization failed to elicit an adequate secretory response from the mast cells of rats in which the release of adrenocorticotropic hormone had been blocked by dexamethasone.
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 120, No 10, pp. 349–351, October, 1995
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Shapiro, F.B., Umarova, B.A. & Strukova, S.M. Role of adrenocorticotropic hormone in the activation of heparin secretion by mast cells in stressed rats. Bull Exp Biol Med 120, 981–983 (1995). https://doi.org/10.1007/BF02444961
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DOI: https://doi.org/10.1007/BF02444961