Abstract
Examination of the reactivity exhibited by the basilar artery of the brain in Krushinsky-Molodkina rats before and after an induced epileptiform seizure accompanied by subarachnoid hemorrhages showed increased contractility of this artery in response to endothelin-1 and its reduced sensitivity to ATP 24 h after the seizure. Such changes in the reactivity of brain vessels may contribute to the development of vasospasm and secondary ischemia of the brain after an epileptic seizure.
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 121, No 2, pp. 131–134, February, 1996
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Storozhevykh, T.P., Pinelis, V.G., Koshelev, V.B. et al. Reactivity of the basilar artery in Krushinsky-Molodkina rats 24 hours after an audiogenic epileptic seizure. Bull Exp Biol Med 121, 120–123 (1996). https://doi.org/10.1007/BF02446613
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DOI: https://doi.org/10.1007/BF02446613