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Effect of storage of platelet concentrate and products of myeloperoxidase reaction on initial platelet aggregation

  • Biophysics and Biochemistry
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

An original nephelometric method allows one to measure initial platelet aggregation after a long-term storage of platelet concentrate. This attests to a high level of platelet activity despite the fact that final platelet aggregation cannot be detected by usual turbidimetric method. N-chloroalanine more slowly inhibits initial platelet aggregation in comparison with sodium hypochlorite, which implies different mechanisms of their membrane-modifying effects.

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Authors and Affiliations

  1. Institute of Physicochemical Medicine, Russian State Medical University, Moscow

    D. I. Roshchupkin, V. V. Berzhitskaya, A. Yu. Sokolov & M. A. Murina

Authors
  1. D. I. Roshchupkin
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  2. V. V. Berzhitskaya
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  3. A. Yu. Sokolov
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  4. M. A. Murina
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Additional information

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 124, No. 11, pp. 523–526, November, 1997

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Roshchupkin, D.I., Berzhitskaya, V.V., Sokolov, A.Y. et al. Effect of storage of platelet concentrate and products of myeloperoxidase reaction on initial platelet aggregation. Bull Exp Biol Med 124, 1081–1084 (1997). https://doi.org/10.1007/BF02445667

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  • DOI: https://doi.org/10.1007/BF02445667

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