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Effect of nitro derivatives on electromechanical coupling in ureteral smooth muscle cells

  • Biophysics and Biochemistry
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Double sucrose gap experiments revealed differences in the effect of nitroglycerin and sodium nitroprusside on action potential and contraction of ureteral smooth muscle cells. Unlike sodium nitroprusside, nitroglycerin inhibited voltage-dependent Ca2+ membrane permeability. It was concluded that cGMP-independent mechanisms of the effects of nitro derivative reflect the peculiarities of excitation-contraction coupling in smooth muscles.

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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 129, No. 5, pp. 539–541, May, 2000

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Kovalev, I.V., Popov, A.G., Panov, A.A. et al. Effect of nitro derivatives on electromechanical coupling in ureteral smooth muscle cells. Bull Exp Biol Med 129, 455–457 (2000). https://doi.org/10.1007/BF02439800

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  • DOI: https://doi.org/10.1007/BF02439800

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