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The use of large-scale cDNA analysis to profile differential gene expression in KYSE 410 human esophageal cancer cells after irradiation

  • Genetics
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Atlas Human cDNA Expression Array, which includes 588 genes divided into functional classes, was used to study gene expression profiles in KYSE 410 human esophageal cancer cells irradiated in doses of 6 and 18 Gy. Considerable changes in the expression of a number of genes was found, including down-regulation of 3 cell cycle regulators and up-regulation of an apoptosis-related gene. Comparison of the expression profiles and identification of genes were performed with Atlas Vision 3.0 software.

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References

  1. Atlas Human cDNA Expression Array I, CLONTECHniques, 12, No. 2, 4–7 (1997).

  2. Atlas Vision 3.0 Software, Ibid. CLONTECHniques, 13, No. 1, 4 (1998).

  3. A. Chlenchik, S. Chen, M. Makhanov, and P. Siebert, Ibid.Atlas Vision 3.0 Software, CLONTECHniques, 13, No. 1 pp. 16–17. (1998).

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Correspondence to J. L. Sebastian.

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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 130, No. 9, pp. 313–316, September, 2000

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Sebastian, J.L., Rigberg, D.A., Shrivatsan, E. et al. The use of large-scale cDNA analysis to profile differential gene expression in KYSE 410 human esophageal cancer cells after irradiation. Bull Exp Biol Med 130, 882–885 (2000). https://doi.org/10.1023/A:1015374530823

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  • DOI: https://doi.org/10.1023/A:1015374530823

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