Summary
Preparative methods have been worked out for the bromination of unprotected deoxy-AMP, deoxy-GMP, and deoxy-CMP and methods have been devised for the isolation and purification of the bromine derivatives.
Some physicochemical characteristics (UV spectra, Rf values on thin-layer and paper chromatography, coefficients of millimolar extinction) of the bromine derivatives of the DNA components obtained have been determined.
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Additional information
Moscow. Translated from Khimiya Prirodnykh Soedinenii, No. 4, pp. 524–527, July–August, 1976.
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Marchenkov, N.S., Mikhailov, K.S., Orlova, V.A. et al. Halogenation of the components of nucleic acids. Chem Nat Compd 12, 464–466 (1976). https://doi.org/10.1007/BF00564810
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DOI: https://doi.org/10.1007/BF00564810