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Synthesis of biologically active analogs of luliberin with shortened amino acid sequences

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Abstract

Two new analogs of the releasing factor of the luteinizing hormone with shortened amino acid sequences have been synthesized by the methods of classical peptide chemistry. The influence of the preparations on the action of chorionic gonadotropin and on the course of processes of ovulation in experimental animals has been studied. The promising nature in this direction of the search for active analogs for luliberin has been shown.

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A. A. Zhdanov Leningrad State University. N. N. Petrov Scientific-Research Institute of Oncology, Ministry of Health of the USSR, Leningrad. Institute of Obstetrics and Gynecology, Academy of Medical Sciences of the USSR. Ministry of Public Health of the USSR, Leningrad. Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 768–773, November–December, 1982.

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Burov, S.V., Nikolaev, S.V., Smironova, M.P. et al. Synthesis of biologically active analogs of luliberin with shortened amino acid sequences. Chem Nat Compd 18, 732–737 (1982). https://doi.org/10.1007/BF00579436

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  • DOI: https://doi.org/10.1007/BF00579436

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