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Deuterium-labeled choline: Lack of isotope effects during the synthesis and catabolism of acetylcholine in vivo

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References

  1. Hanin, I., andSchuberth, J. 1974. Labelling of acetylcholine in the brain of mice fed on a diet containing deuterium labelled choline: Studies ultilizing gas chromatography mass spectrometry. J. Neurochem. 23:819–824.

    PubMed  Google Scholar 

  2. Costa, F., Cheney, D. L., Racagni, G., andZsilla, G. 1975. An analysis at synaptic level of the morphine action in striatum and N. accumbens: Dopamine and acetylcholine interactions. Life Sci. 17:1–8.

    PubMed  Google Scholar 

  3. Jenden, D. J., Choi, L., Silverman, R. W., Steinborn, J. A., Roch, M., andBooth, R. A. 1974. Acetylcholine turnover estimation in brain by gas chromatography/mass spectrometry. Life Sci. 14:55–63.

    PubMed  Google Scholar 

  4. Chao, L.-P., andWolfgram, F. 1973. Purification and some properties of choline acetyltransferase (EC 2.3.1.6) from bovine brain. J. Neurochem. 20:1075–1081.

    PubMed  Google Scholar 

  5. Schrier, B. K., andShuster, L. 1967. A simplified radiochemical assay for choline acetyltransferase. J. Neurochem. 14:977–985.

    PubMed  Google Scholar 

  6. Chan, S. L., Shirachi, D. Y., andTrevor, A. J. 1972. Purification and properties of brain acetylcholinesterase (EC 3.1.1.7). J. Neurochem. 19:437–447.

    PubMed  Google Scholar 

  7. Hanin, I., Massarelli, R., andCosta, E. 1972. An approach to the in vivo study of acetylcholine turnover in rat salivary glands by radio gas chromatography. J. Pharmacol. Exp. Ther. 181:10–18.

    PubMed  Google Scholar 

  8. Potter, L. T., andMurphy, W. 1967. Electrophoresis of acetylcholine, choline and related compounds. Biochem. Pharmacol. 16:1386–1388.

    PubMed  Google Scholar 

  9. McCaman, M. W., Tomey, L. R., andMcCaman, R. E. 1968. Radiomimetric assay of acetylcholinesterase activity in submicrogram amounts of tissue. Life Sci. 7:233–244.

    PubMed  Google Scholar 

  10. Lowry, O. H., Rosebrough, N. H., Farr, A. L., andRandall, R. J. 1951. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193:265–275.

    PubMed  Google Scholar 

  11. Simon, J. R., Mittag, T. W., andKuhar, M. J. 1975. Inhibition of synaptosomal uptake of choline by various choline analogs. Biochem. Pharmacol. 24:1139–1142.

    PubMed  Google Scholar 

  12. Kuhar, M. J., Sethy, V. H., Roth, R. H., andAghajanian, G. K. 1973. Choline: Selective accumulation by central cholinergic neurones. J. Neurochem. 20:581–593.

    PubMed  Google Scholar 

  13. Bowery, N. G., andNeal, M. J. 1975. Failure of denervation to influence the high affinity uptake of choline by sympathetic ganglia. Br. J. Pharmacol. 55:278P.

    Google Scholar 

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Garrison-Gund, C.K., Neff, N.H. Deuterium-labeled choline: Lack of isotope effects during the synthesis and catabolism of acetylcholine in vivo. Neurochem Res 1, 679–682 (1976). https://doi.org/10.1007/BF00965608

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