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Zur Isolierung von 18-Aldosteronglucuronid und Tetrahydroaldosteronglucuronid aus menschlichem Urin

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Zusammenfassung

Zur Isolierung von Tetrahydroaldosteronglucuronid und 18-Aldosteronglucuronid aus menschlichem Urin wird eine Kombination von verschiedenen Methoden angegeben, und die einzelnen Schritte werden diskutiert. Die Ausbeute für das Tetrahydroaldosteronglucuronid beträgt 80% und für das 18-Aldosteronglucuronid knapp 50%.

Summary

18-aldosterone glucuronide and tetrahydroaldosterone glucuronide were isolated from human urine by ether-ethanol extraction, column chromatography on alumina and paper chromatography with two different solvent systems. The yields were nearly 50% for 18-aldosterone glucuronide and 80% for tetrahydroaldosterone glucuronide.

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Authors and Affiliations

  1. Medizinische Universitäts-Poliklinik Zürich, Switzerland

    J. Möhring

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Diese Arbeit wurde durch die Hilfe des Schweizerischen Nationalfonds zur Förderung der wissenschaftlichen Forschung und der Stiftung für wissenschaftliche Forschung an der Universität Zürich ermöglicht.

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Möhring, J. Zur Isolierung von 18-Aldosteronglucuronid und Tetrahydroaldosteronglucuronid aus menschlichem Urin. Klin Wochenschr 46, 18–21 (1968). https://doi.org/10.1007/BF01725293

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