Skip to main content
SpringerLink
Log in

Ascorbinsäuregehalt im Plasma und in Leukozyten bei Patienten mit chronischer Hämodialysebehandlung

Ascorbic acid content in plasma and in leukocytes in patients undergoing maintenance haemodialysis

  • Kurze Wissenschaftliche Mitteilungen
  • Published:
Klinische Wochenschrift Aims and scope Submit manuscript

Summary

Patients undergoing maintenance haemodialysis exhibited at a regular level of ascorbic acid in plasma a decreased concentration of ascorbic acid in leukocytes. Therefore, the ascorbic acid should be administered in a high dosage to patients undergoing chronic haemodialysis, in order to prevent a vitamin-C deficiency in leukocytes.

Zusammenfassung

Patienten mit chronischer Hämodialysebehandlung zeigten bei einem regelrechten Ascorbinsäurewert im Plasma eine herabgesetzte Konzentration der Ascorbinsäure in den Leukozyten. Daher sollte die Ascorbinsäure diesen Patienten in hoher Dosierung zugeführt werden, um einen Vitamin-C-Mangel in den Leukozyten zu verhindern.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Literatur

  1. Andrews, J., Brook, M.: Relationship of plasma and leucocyte (including platelets) ascorbic acid contents. Geront. clin.10, 128 (1968)

    Google Scholar 

  2. Barthelmai, W., Vetrella, M., Eschenbach, C., Jehn, E.: Leukozytenisolierung aus kleinen Blutvolumina. Klin. Wschr.49, 263 (1971)

    Google Scholar 

  3. Bradley, D.W., Maynard, J.E., Webster, H.: Plasma and whole blood concentrations of ascorbic acid in patients undergoing longterm hemodialysis. Am. J. clin. Pathol.60, 145 (1973)

    Google Scholar 

  4. Griffiths, L.L., Brocklehurst, J.C., Scott, D.L., Marks, J., Blakkley, J.: Thiamine and ascorbic acid levels in the elderly. Geront. clin.9, 1 (1967)

    Google Scholar 

  5. Loh, H.S., Wilson, C.W.M.: The origin of ascorbic acid stored in the leucocytes. Brit. J. Pharmacol.40, 169 (1970)

    Google Scholar 

  6. Loh, H.S., Wilson, C.W.M.: Relationship between leucocyte and plasma ascorbic acid concentrations. Brit. med. J.3, 733 (1971)

    Google Scholar 

  7. Recommended dietary allowances. National Academy of Sciences, p. 1, Washington (1968)

  8. Smith, E.K.M., Welt, L.G.: The red blood cell as a model for the study of uremic toxins. Arch. Intern. Med.126, 827 (1970)

    Google Scholar 

  9. Sullivan, J.F., Eisenstein, A.B.: Ascorbic acid depletion during hemodialysis. JAMA,220, 1697 (1972)

    Google Scholar 

  10. Wilson, C.W.M.: Die metabolische Bereitstellung von Vitamin C in Vitamine, Editiones „Roche“, S. 75, Hoffmann-La-Roche A.G., Grenzach (1972)

    Google Scholar 

  11. Zannoni, V., Lynch, M., Goldstein, S., Sato, P.: A rapid micromethod for the determination of ascorbic acid in plasma and tissues. Biochem. Med.11, 41 (1974)

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Abteilung für innere Medizin mit Schwerpunkt Nephrologie und klinisch-chemisches Zentrallabor des Klinikum Charlottenburg der Freien Universität Berlin, Germany

    P. Froese, J. Hermeyer & M. Kessel

Authors
  1. P. Froese
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. Hermeyer
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. M. Kessel
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Froese, P., Hermeyer, J. & Kessel, M. Ascorbinsäuregehalt im Plasma und in Leukozyten bei Patienten mit chronischer Hämodialysebehandlung. Klin Wochenschr 55, 1173–1174 (1977). https://doi.org/10.1007/BF01478055

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01478055

Key words

Schlüsselwörter

Search

Navigation