Summary
We report our results on 9 patients with disseminated malignant melanoma, treated with combination of DDP and IF, 3 in addition with VD. In none of them a complete remission was obtained, the median survival was 4.2 months. These disappointing results, in addition to the rather toxic side effects from the chemotherapy, do not present any benefit over less toxic regimens.
Zusammenfassung
Es wird über 9 Melanompatienten im klinischen Stadium III berichtet, die mit DDP und IF, 3 davon zusätzlich mit VD behandelt wurden. In keinem Fall konnte eine komplette Remission erreicht werden, die mittlere Überlebenszeit betrug 4,2 Monate. Unter Berücksichtigung der Nebenwirkungen bietet diese Kombinationschemotherapie keinen Vorteil gegenüber weniger toxischer Maßnahmen.
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Balda, B.R., Jehn, U., Klövekorn, W. et al. Kombinationschemotherapie maligner Melanome mit cis-Diamino-dichloro-platin (II) und Ifosfamid. Klin Wochenschr 59, 781–786 (1981). https://doi.org/10.1007/BF01724683
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DOI: https://doi.org/10.1007/BF01724683