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Der Einfluß von Narkose und Operation auf das Immunsystem

Literaturübersicht

The effect of anaesthesia and surgery on immune function

A review

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Summary

This paper reviews the literature concerning the question, how the immune functions might be affected by anaesthesia and surgery.

General and local anaesthetics inhibit in vitro and in vivo important functions of lymphocytes, granulocytes, and macrophages. However, the postoperative immunosuppression is not attributable to the anaesthesia but rather appears to depend on the tissue truma itself.

Zusammenfassung

Die vorliegende Arbeit untersucht anhand der Literatur die Frage, durch welche Faktoren das menschliche Immunsystem im Zusammenhang mit Operationen beeinflußt wird. Narkotika und Lokalanästhetika vermögen in vitro und in vivo wichtige Funktionen der Lymphozyten, Granulozyten und Makrophagen zu hemmen. Trotzdem ist die postoperative Immunsuppression nicht durch den Einfluß der Narkose zu erklären. Die Hemmung der zellulären Immunität nach Operationen hängt offenbar einzig vom Operationstrauma selbst ab.

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Authors and Affiliations

  1. Universitäts-Hautklinik Münster, Germany

    E. B. Bröcker & E. Macher

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  1. E. B. Bröcker
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  2. E. Macher
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Bröcker, E.B., Macher, E. Der Einfluß von Narkose und Operation auf das Immunsystem. Klin Wochenschr 59, 1297–1301 (1981). https://doi.org/10.1007/BF01711179

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  • DOI: https://doi.org/10.1007/BF01711179

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