Summary
In order to evaluate the prevalence of renal artery stenoses and the coincidence with hypertension, in this study 110 patients (24 women, 86 men, mean age 63.2±8.6 years) underwent retrograde aortography for reason of symptomatic arteriosclerosis obliterans of the lower limb arteries. In 18 (16.4%) patients renal artery stenoses by which the lumen was narrowed for more than 30% and in 2 (1.8%) patients occlusions of one renal artery were found, all of which seemed to be of arteriosclerotic origin. 12 (60%) patients with renal artery stenoses or occlusions showed arterial hypertension (RR 171±33/94±16 mmHg) inspite of adequate antihypertensive medication, 8 were normotensive even though renal artery stenoses were found angiographically. On the other hand 30 (33%) of the 90 patients without renal artery stenoses were hypertensive (RR 165±15/93±9 mmHg). These data support the observation that renal artery stenoses must not result in hypertension, but clearly indicate the higher prevalence of hypertension in patients with renal artery stenoses or occlusions. With regard to the low-risk procedure of percutaneous transluminal dilatation of renal arteries, it seems to be valuable for hypertensive patients to include renovasography into the angiographic evaluation of symptomatic lower limb arteriosclerosis.
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Literatur
Zuber J, Lüscher T, Vetter W (1980) Renovaskuläre Hypertonie in der Schweiz 1976–1978. Eine Multicenter-Studie. Schweiz Med Wochenschr 110:1096
Grüntzig A, Kuhlmann U, Vetter W, Lütolf U, Meier B, Siegenthaler W (1978) Treatment of renovascular hypertension with percutaneous transluminal dilatation of a renal artery stenosis. Lancet 1:801
Kuhlmann U, Vetter W, Furrer J, Lütolf U, Siegenthaler W, Grüntzig A (1980) Renovascular hypertension: Treatment by percutaneous transluminal dilatation. Ann Intern Med 92:1
Mahler F, Krneta A, Haertel M (1979) Treatment of renovascular hypertension by transluminal renal artery dilatation. Ann Intern Med 90:56
Tegtmeyer CY, Teates CD, Crigler N, Gandee RW, Ayers CR, Stoddard M, Wellons HK (1981) Percutaneous transluminal angioplasty in patients with renal artery stenosis. Radiology 140:323
Kuhlmann U, Vetter W, Grüntzig A, Schneider E, Pouliadis G, Steurer J, Siegenthaler W (1981) Percutaneous transluminal dilatation of renal artery stenosis: 2 years experience. Clin Sci 61:481s
Greminger P, Vetter W, Lüscher T, Schneider E, Vetter H, Largiadèr F, Pouliadis G, Siegenthaler W, Kuhlmann U (1982) Renovaskuläre Hypertonie: Vergleich zwischen transluminaler Dilatation und operativen Verfahren. Schweiz Med Wochenschr 112:1344
Greminger P, Kuhlmann U, Vetter W, Grüntzig A, Schneider E, Pouliadis G, Wehling M, Neyses L, Siegenthaler W (1982) Langzeitverläufe nach perkutaner transluminaler Dilatation von Nierenarterienstenosen. VASA 4:362
Eyler WR, Clark MD, Garman JE, Rian RL, Meiniger DE (1962) Angiography of the renal areas including a comparative study of renal arteria stenoses in patients with and without hypertension. Radiology 78:879
Hunt JC, Sheps SG, Harrison EG, Strong CG, Bernatz PE (1974) Renal and renovascular hypertension: A: Reasoned approach to diagnosis and management. Arch Intern Med 133:988
Wylie EJ, Perloff D, Willington JS (1962) Fibromuscular hyperplasia of the renal arteries. Ann Surg 156:592
Amsterdam EA, Couch NP, Christlieb AR, Harrison JH, Crane Ch, Dobrizinsky SJ, Hickler RB (1969) Renal vein renin activity in the prognosis of surgery for renovascular hypertension. Am J Med 47:860
Bourgoignie J, Kurz S, Catanzaro FJ, Serirat P, Perry HM (1970) Renal venous renin in hypertension. Am J Med 48:332
Vaughan ED, Bühler FR, Laragh JH, Sealey JE, Baer L, Bard RH (1973) Renovascular hypertension: Renin, measurements to indicate hypersecretion and contralateral suppression, estimate renal plasma flow and score for surgical curability. Am J Med 55:402
Marks LS, Maxwell MH, Varady PD, Lupu AN, Kaufman JJ (1976) Renovascular hypertension: Does the renal vein renin ratio predict operative results? Urol (Baltimore) 115:365
Vetter W, Vetter H, Kuhlmann U, Studer A, Glänzer K, Pouliadis G, Largiadèr F, Siegenthaler W (1979) Renovaskuläre Hypertonie: Prognostischer Wert der seitengetrennten Reninbestimmung im Nierenvenenblut. Klin Wochenschr 57:863
Marks LS, Maxwell MH, Kaufmann JJ (1979) Non-reninmediated renovascular hypertension: A new syndrome? Lancet I:616
Maxwell MH (1975) Cooperative study of renovascular hypertension: Current status. Kidney Int 8:153
Foster JH, Maxwell MH, Franklin SS, Bleifer KH, Trippel OH, Julian OC, De Camp PT, Varady PT (1975) Renovascular occlusive disease. Results of operative treatment. JAMA 231:1043
Stanley JC, Fry WJ (1977) Surgical treatment of renovascular hypertension. Arch Surg 112:1291
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Kuhlmann, U., Wehling, M., Vetter, W. et al. Häufigkeit und Bedeutung von Nierenarterienstenosen bei Patienten mit peripherer arterieller Verschlußkrankheit. Klin Wochenschr 61, 339–342 (1983). https://doi.org/10.1007/BF01485024
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DOI: https://doi.org/10.1007/BF01485024