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Hypothermia in Hodgkin's disease after exploratory laparotomy

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Summary

Hypothermia is a rare complication of unknown origin in Hodgkin's disease which has been reported after the administration of antineoplastic agents, chlorpromazine and paracetamol. We report a highly febrile patient with stage IV-B Hodgkin's disease of mixed cellularity type who underwent exploratory laparotomy. Because of suspected septic shock high-dose prednisolone was given during surgery. Postoperatively the patient's body temperature fell progressively to 32.9° C and remained at less then 35.5° C for the following 5 days. There seems to be some functional disorder of thermoregulation in Hodgkin's disease. Physical factors during surgery or certain drugs, especially cytotoxics, corticosteroids, anesthetics or antipyretics may lead to prolonged hypothermia.

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Abbreviations

Gamma-GT:

Gamma-glutaryl transpeptidase

MOPP:

combined chemotherapy consisting of nitrogen mustard, vincristine, procarbazine, and prednisolone

SGOT:

Serum-glutamate-oxalacetate transaminase

SGPT:

Serum-glutamate-pyruvate transaminase

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Jung, M., Koppensteiner, R., Graninger, W. et al. Hypothermia in Hodgkin's disease after exploratory laparotomy. Klin Wochenschr 66, 552–555 (1988). https://doi.org/10.1007/BF01736525

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  • DOI: https://doi.org/10.1007/BF01736525

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