Summary
Hypothermia is a rare complication of unknown origin in Hodgkin's disease which has been reported after the administration of antineoplastic agents, chlorpromazine and paracetamol. We report a highly febrile patient with stage IV-B Hodgkin's disease of mixed cellularity type who underwent exploratory laparotomy. Because of suspected septic shock high-dose prednisolone was given during surgery. Postoperatively the patient's body temperature fell progressively to 32.9° C and remained at less then 35.5° C for the following 5 days. There seems to be some functional disorder of thermoregulation in Hodgkin's disease. Physical factors during surgery or certain drugs, especially cytotoxics, corticosteroids, anesthetics or antipyretics may lead to prolonged hypothermia.
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Abbreviations
- Gamma-GT:
-
Gamma-glutaryl transpeptidase
- MOPP:
-
combined chemotherapy consisting of nitrogen mustard, vincristine, procarbazine, and prednisolone
- SGOT:
-
Serum-glutamate-oxalacetate transaminase
- SGPT:
-
Serum-glutamate-pyruvate transaminase
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Jung, M., Koppensteiner, R., Graninger, W. et al. Hypothermia in Hodgkin's disease after exploratory laparotomy. Klin Wochenschr 66, 552–555 (1988). https://doi.org/10.1007/BF01736525
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DOI: https://doi.org/10.1007/BF01736525