Summary
We have studied the fate of diabetic neuropathy and autonomic function in 13 patients with long standing Type 1 (insulin-dependent) diabetes mellitus following combined pancreas and kidney transplantation. Fifteen diabetic patients with a kidney graft only served as controls. After initial improvement of the neuropathy in both groups, probably caused by the elimination of uraemia, a continuous improvement during the 48 months study was seen in the euglycaemic pancreas graft recipients only. Autonomic (parasym-pathetic) function improved only slightly and to a similar extent in both groups.
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Solders, G., Tydén, G., Persson, A. et al. Improvement in diabetic neuropathy 4 years after successful pancreatic and renal transplantation. Diabetologia 34 (Suppl 1), S125–S127 (1991). https://doi.org/10.1007/BF00587637
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DOI: https://doi.org/10.1007/BF00587637