Summary
The present report concerns investigation of bladder disturbances in 31 juvenile diabetics. It was shown that: 1. The predominant lesion is one of neuropathy. — 2. Vesical involvement such as increased capacity and atony was demonstrated by cystometry in 27 out of the 31 cases (87%). — 3. 4 cases had neck hypertrophy. — 4. The most striking symptom was a large volume of first morning urine. This information was elicited from the patients. They had no urological complaints. — 5. A high incidence of impotence was seen in diabetics with neurogenic bladder. — 6. The possible causes of such lesions and the value of certain therapeutic measures was discussed.
Résumé
Le présent travail concerne une investigation sur les troubles de la vessie chez 31 diabétiques jeunes. Il a été démontré que: 1. La lésion prédominante est une lésion de neuropathie. — 2. Des signes vésicaux tels que la capacité accrue et l'atonie mesurées par cystométrie, ont été démontrés dans 27 cas sur les 31 (87%). — 3. 4 cas avaient une hypertrophie du col. — 4. Le symptome le plus frappant était l'important volume de la première urine du matin. Ceci a été indiqué par les patients. Ils ne se plaignaient d'aucun trouble urologique. — 5. On trouve une haute fréquence d'impuissance chez les diabétiques ayant une vessie neurogène. — 6. Les causes possibles de telles lésions et la valeur de certaines mesures thérapeutiques sont discutées.
Zusammenfassung
Es wird über Blasenstörungen bei 31 jugendlichen Diabetikern berichtet. Es konnte gezeigt werden, daß: 1. die Neuropathie die vorherrschende Störung darstellt; 2. bei 27 von 31 Fällen (87%) eine Blasenbeteiligung (gesteigerte Kapazität und zytometrisch nachweisbare Atonie) vorlag; — 3. bei 4 Fällen eine Blasenhalshypertrophie bestand; — 4. hervorstechendes Symptom war die große Harnmenge bei der ersten morgendlichen Blasenentleerung, über das die Patienten auf Anfrage berichteten. Sie äußerten keine urologischen Beschwerden; — 5. Bei vielen Diabetikern mit einer neurogenen Blasenstörung ist eine Impotenz festzustellen; — 6. Die für diese Läsionen in Frage kommenden Ursachen und der Wert einiger therapeutischer Maßnahmen werden diskutiert.
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References
Balfour, J., Ankenman, G.J.: Atonic neurogenic bladder as a manifestation of diabetic neuropathy. J. Urol. (Baltimore)76, 746–752 (1956).
Bischoff, A.: New morphologic and pathogenetic aspects of diabetic neuropathy, p. 627. Diabetes. Ed. J. Ostman. Excerpta med. Found. I.C.S. 172. Amsterdam: 1969.
Bors, E., Comar, E.: Neurological disturbances of sexual function with special references to 529 patients with spinal cord injury. Urol. Surv.10, 191–222 (1960).
Boyarsky, S.: Neurogenic bladder. Symposium. Ed. Wilkins-Wilkins. Baltimore: 1967.
Campos, C.A., Diaz Colodrero, A.: Estudios sobre la vejiga diabética. Rev. Asoc. méd. argent.61, 669–672 (1947).
Cibeira, J.B., Dominelli, J.C., Buzzi, A.: Estudios clinicos y electromiograficos en 110 pacientes tratados con un derivado de las benzodiazepinas. La Prensa méd. argent.51, 1544–1572 (1964).
—, Cursillo de electromiografia. Rev. Asoc. méd. argent.80, 560–567 (1966).
Coers, C., Hildebrand, J.: Latent neuropathy in diabetic and alcoholism. Neurology (Minneap.)15, 19–38 (1965).
Colby, A. O.: Neurologic disorders of diabetes mellitus.14, 424–429 (1965).
—: Neurologic disorders of diabetes mellitus. Diabetes14, 516–525 (1965).
Eliasson, S.G.: Changes in nerve lipid metabolism in experimental diabetes, p. 620. Diabetes. Ed. J. Ostman. Excerpta med. Found. I.C.S. 172. Amsterdam: 1969.
Ellenberg, M.: Diabetic neurogenic vesical disfunction. A.M.A. Arch. intern. Med.117, 348–354 (1966).
—: The incipient asyntomatic bladder. Diabetes16, 331–335 (1967).
—: Present status of diabetic neuropathy, p. 615. Diabetes. Ed. J. Ostman. Excerpta med. Found. I.C.S. 172. Amsterdam: 1969.
Faerrnan, I., Maler, M., Jadzinsky, M.N., Fox, D., Alvarez, E., Zilverbarg, J., Cibeira, J.B., Colinas, R.: Vejiga neurogénica en diabeticos. Rev. Soc. argent. Urol.38, 16–28 (1969).
Fagerberg, S.: Recent advances in diabetic neuropathy. On the nature and treatment of diabetes, p. 522. Ed. Leibel, B.S., Wrenshall, G. A. Excerpta med. Found. 84. Amsterdam: 1965.
—: A study of the urinary bladder in diabetic males and controls, p. 646. Diabetes. Ed. J. Ostman. Excerpta. Med. Found. I.C.S. 172. Amsterdam: 1969.
Field, R.: Altered nerve metabolism in diabetes, p. 617. Diabetes. Ed. J. Ostman. Excerpta med. Found. I.C.S. 172. Amsterdam: 1969.
Gregersen, G.: Latency time, maximal amplitude and electromiography in diabetics patients. Acta med. scand.183, 55–60 (1968).
—: Vibratory perception, threshold and motor conduction in diabetics and non diabetics. Acta med. scand.183, 61–65 (1968).
Guzman, J.M.: Vejiga neurogénica. Actas del VIII Congreso Argentino de Urologia, 541–604 (1964).
Jadzinsky, M.N., Faerman, I., Fox, D., Varela, J., Gonzalez Casco, J., Schvartzman, R.: Tratamiento hormonal de la impotencia sexual del hombre diabético. Día Medico39, 862–863 (1969).
— — —: Lesiones nerviosas en diabetes. Dia Médico39, 1027–1030 (1969).
— — —: Lesiones nerviosas en diabetes. Dia Médico39, 1685–1687 (1969).
Knowles, H., Guest, G., Lampe, R., Kessler, M.: The course of juvenile diabetic treated with unmeasured diet. Diabetes14, 239–273 (1965).
Larcan, A., Huriet, G., Vaillandet, M., Fauchier, J.P.: Les manifestations vesicales au course du diabete. La Presse Medicale75, 273–276 (1965).
Larsson, Y., Sterky, C.: Long term prognosis in juvenile diabetes mellitus. Acta Paediat. (Uppsala)51, Suppl.130, 5–76 (1961).
Marble, A.: Therapy; criteria of control. Diabetes. Mellitus, Diagnosis and Treatment. Ed. Amer. D. Assoc. N. York1, 69–71 (1964).
—, Angiopathy in diabetes, an unsolved problem. Diabetes16, 825–838 (1967).
Martin, M.: Involvement of autonomic fibers in diabetic neuropathy. Lancet6760, 560–565 (1963).
Mouren, P., Serratrice, G., Tatossian, A.: Les manifestations nerveux des diabétiques, p. 66. Grenoble: Masson et Cie 1966.
Pirart, J.: Diabetic neuropathy, a metabolism or a vascular disease. Diabetes14, 1–9 (1965).
—, Coers, C.: Diabetic neuropathy, a critical appraisal, p. 633. J. Ostman. Excerpta med. Found. I.C.S. 172. Amsterdam: 1969.
Schoffling, K., Federlin, K., Ditschuneit, H., Pfeiffer, B.F.: Disorders of sexual function in male diabetics. Diabetes12, 519–527 (1963).
—: Hypogonadism in male subjets. On the nature and treatment of diabetes, p. 505. Ed. Leibel, B.S., Wrenshall, G.A. Excerpta med. Found. I.C.S. 84. Amsterdam: 1965.
Sprague, R.G.: Impotence in male diabetics. Diabetes12, 559–560 (1963).
Thomas, P.K., Lascelles, R.G.: The pathology of diabetic neuropathy. Quarterly. J. Med.35, 489–509 (1966).
World Health Organitation (W.H.O.): Technical series report. Diabetes mellitus.310, 13–15 (1965).
Woolrch, J., Garda, R.: Retencion vesical y vejiga neurogénica en la mujer. Rev. Mex. Urol.28, 183–190 (1968).
Yamagata, S., Yamauchi, Y.: Diabetic neuropathy and triopathy. p. 649. Ed. J. Ostman. Excerpta Med. Found. I.C.S. 172. Amsterdam: 1969.
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Faerman, I., Maler, M., Jadzinsky, M. et al. Asymptomatic neurogenic bladder in juvenile diabetics. Diabetologia 7, 168–172 (1971). https://doi.org/10.1007/BF01212549
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DOI: https://doi.org/10.1007/BF01212549