Abstract
Dimethyl sulfide in breath was determined by the gas chromatographic method in 14 persons exposed to organic reduced sulfur compounds in sulfate pulp mills. Dimethyl sulfide concentrations in breath (range 0.04–0.69 cm3/m3 were compared to the combined work-place concentrations of methyl mercaptan, dimethyl sulfide and dimethyl disulfide. This method of analysis proved to be a practical noninvasive way to assess recent exposure, and therefore it should be applicable to workplaces contaminated with organic sulfur compounds in the pulp industry.
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Al Mardini H, Leonard J, Bartlett K, Lloyd S, Record CO (1988) Effect of methionine loading and endogenous hypermethioninaemia on blood mercaptans in man. Clin Chim Acta 176: 83–90
Blom HJ, Tangerman A (1988) Methanethiol metabolism in whole blood. J Lab Clin Med 111: 606–610
Blom HJ, Chamuleau RAFM, Rothuizen J, Deutz NEP, Tangerman A (1990) Methanethiol metabolism and its role in the pathogenesis of hepatic encephalopathy in rats and dogs. Hepatology 11: 682–689
Dawson JH, Andersson LA, Sono M (1983) The diverse spectroscopic properties of ferrous cytochrome P-450-CAM ligand complexes. J Biol Chem 258: 13637–13645
Jaakkola JJK, Vilkka V, Marttila O, Jäppinen P, Haahtela T (1990) The South Karelia air pollution study: the effects of malodorous sulfur compounds from pulp mills on respiratory and other symptoms. Annu Rev Respir Dis 142: 1344–1350
Jäppinen P, Tenhunen R (1990) Hydrogen sulphide poisoning: blood sulphide concentration and changes in haem metabolism. Br J Ind Med 47: 283–285
Jäppinen P, Tola S (1990) Cardiovascular mortality among pulp mill workers. Br J Ind Med 47: 259–262
Kangas J, Jäppinen P, Savolainen H (1984) Exposure to hydrogen sulfide, mercaptans and sulfur dioxide in pulp industry. Am Ind Hyg Assoc J 45: 787–790
Kangas J, Nevalainen A, Manninen A, Savolainen H (1986) Ammonia, hydrogen sulfide and methyl mercaptides in Finnish municipal sewage plants and pumping stations. Sci Tot Environ 57: 49–55
Liesivuori J, Savolainen H (1987) Urinary formic acid as an indicator of occupational exposure to formic acid and methanol. Am Ind Hyg Assoc J 48: 32–34
Namiesnik J (1984) Generation of standard gaseous mixtures. J Chromatogr 100: 79–108
Polak E, Fetison G, Fombon A-M, Skalli A (1988) Structure-odor relationships for “catty”-smelling mercapto compounds in humans. J Agric Fd Chem 36: 355–359
Susman JL, Hornig JF, Thomas SC, Smith RP (1978) Pulmonary excretion of hydrogen sulfide, methanethiol, dimethyl sulfide and dimethyl disulfide in mice. Drug Chem Toxicol 1: 327–338
Terazawa K, Kaji H, Akabane H, Takatori T (1991) Determination of dimethyl sulphide in blood and adipose tissue by headspace gas analysis. J Chromatogr Biomed Appl565: 453–456
Wever R, van Gelder BF, Dervatanian DV (1975) Biochemical and biophysical studies on cytochrome c oxidase. XX. Reaction with sulphide. Biochim Biophys Acta 387: 189–199
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Jäppinen, P., Kangas, J., Silakoski, L. et al. Volatile metabolites in occupational exposure to organic sulfur compounds. Arch Toxicol 67, 104–106 (1993). https://doi.org/10.1007/BF01973679
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DOI: https://doi.org/10.1007/BF01973679