Abstract
In a double-blind clinical study, electrocardiogram, blood pressure and systolic time intervals were measured in 40 depressive patients treated with either paroxetine (30 mg/day) or amitriptyline (150 mg/day) for 6 weeks. While amitriptyline significantly increased the heart rate, the QTc interval and the PEP/LVET ratio, paroxetine did not alter any of the cardiovascular parameters measured.
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Kuhs, H., Rudolf, G.A.E. Cardiovascular effects of paroxetine. Psychopharmacology 102, 379–382 (1990). https://doi.org/10.1007/BF02244107
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DOI: https://doi.org/10.1007/BF02244107