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The effects of haloperidol on the EEG spectrum

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Abstract

A placebo-controlled study with six normal volunteers was carried out using 1 mg haloperidol IM. In some EEG frequency bands, the power density due to haloperidol appeared to increase or decrease depending on the subject. Nevertheless, if the results of the six subjects are taken together, the effects of haloperidol are in agreement with the literature. No correlation was found between plasma concentration of haloperidol and EEG response. Some methodological problems are discussed.

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Authors and Affiliations

  1. Department of Clinical Neurophysiology, State University Utrecht, Utrecht, The Netherlands

    G. H. Wieneke, H. de Wilde & W. Storm van Leeuwen

  2. Department of Psychiatry, State University Utrecht, Utrecht, The Netherlands

    W. M. A. Verhoeven, H. G. M. Westenberg & H. M. van Praag

  3. Bran Research Department, Institute of Medical Physics TNO, Utrecht, The Netherlands

    F. H. Lopes da Silva

Authors
  1. G. H. Wieneke
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  2. W. M. A. Verhoeven
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  3. H. G. M. Westenberg
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  4. H. de Wilde
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  5. F. H. Lopes da Silva
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  6. H. M. van Praag
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  7. W. Storm van Leeuwen
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Wieneke, G.H., Verhoeven, W.M.A., Westenberg, H.G.M. et al. The effects of haloperidol on the EEG spectrum. Psychopharmacology 74, 33–34 (1981). https://doi.org/10.1007/BF00431753

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  • DOI: https://doi.org/10.1007/BF00431753

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