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Responses of the cerebellar cortex to cutaneous and visceral afferents

I. Fiber responses

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Zusammenfassung

Der Zweck der vorliegenden Arbeit war die Beschreibung der Beziehung zwischen den Oberflächen-Evoked Potentials, ausgelöst durch Reizung des N. radialis superficialis und des N. splanchnicus und den evozierten Faserentladungen am Kleinhirn der Katze. Die Entladungen der Moosfasern, Kletterfasern und Axone der Purkinje-Zelle wurden identifiziert und ihre Beziehung zu den Oberflächenpotentialen festgestellt. Die Moosfasern feuern mit Spikesalven und in verschiedenen Gruppen. Diese entsprechen wahrscheinlich Impulsen, die von Fasern mit verschiedener Leitungsgeschwindigkeit fortgeleitet werden und die synchron mit der ersten Positivität der Evoked Potentials sind. Die Kletterfasern stehen in zeitlicher Beziehung zu der Entwicklung der scharfen negativen Ablenkung des EPs und werden zum ersten Male identifiziert. Schließlich weisen die Axone der Purkinje-Zelle dieselben Entladungsmuster auf wie die Purkinje-Zelle selbst. Cutane und viscerale Afferenzen benutzen nicht nur gemeinsame Elemente des cerebellären Cortex, sondern wahrscheinlich auch gemeinsame Leitungswege, obwohl es quantitative Differenzen zwischen beiden Afferenzen gibt.

Summary

To investigate the relationship between the surface evoked potentials of the superficial radial nerve and the splanchnic nerve, and the fiber evoked responses of the cerebellum of the cat was the purpose of the present study. The discharges of the mossy fibers, climbing fibers and Purkinje cell axons were identified and their relationship with the surface-potentials established. The mossy fibers fire with train of spikes in different groups, which probably correspond to impulses transmitted through fibers of different conduction velocities and synchronously with the first positivity of the evoked potential. Climbing fibers respond synchronously with the development of the sharp negative deflection of the evoked potentials and were, for the first time, identified. Finally, the Purkinje cell axons exhibited the same firing pattern as the Purkinje cells. Cutaneous and visceral afferents use not only common elements of the cerebellar cortex but also common pathways, in spite of measurable differences between both afferents.

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Rubia, F.J., Phelps, J.B. Responses of the cerebellar cortex to cutaneous and visceral afferents. Pflugers Arch. 314, 68–85 (1970). https://doi.org/10.1007/BF00587047

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