Zusammenfassung
Der Zweck der vorliegenden Arbeit war die Beschreibung der Beziehung zwischen den Oberflächen-Evoked Potentials, ausgelöst durch Reizung des N. radialis superficialis und des N. splanchnicus und den evozierten Faserentladungen am Kleinhirn der Katze. Die Entladungen der Moosfasern, Kletterfasern und Axone der Purkinje-Zelle wurden identifiziert und ihre Beziehung zu den Oberflächenpotentialen festgestellt. Die Moosfasern feuern mit Spikesalven und in verschiedenen Gruppen. Diese entsprechen wahrscheinlich Impulsen, die von Fasern mit verschiedener Leitungsgeschwindigkeit fortgeleitet werden und die synchron mit der ersten Positivität der Evoked Potentials sind. Die Kletterfasern stehen in zeitlicher Beziehung zu der Entwicklung der scharfen negativen Ablenkung des EPs und werden zum ersten Male identifiziert. Schließlich weisen die Axone der Purkinje-Zelle dieselben Entladungsmuster auf wie die Purkinje-Zelle selbst. Cutane und viscerale Afferenzen benutzen nicht nur gemeinsame Elemente des cerebellären Cortex, sondern wahrscheinlich auch gemeinsame Leitungswege, obwohl es quantitative Differenzen zwischen beiden Afferenzen gibt.
Summary
To investigate the relationship between the surface evoked potentials of the superficial radial nerve and the splanchnic nerve, and the fiber evoked responses of the cerebellum of the cat was the purpose of the present study. The discharges of the mossy fibers, climbing fibers and Purkinje cell axons were identified and their relationship with the surface-potentials established. The mossy fibers fire with train of spikes in different groups, which probably correspond to impulses transmitted through fibers of different conduction velocities and synchronously with the first positivity of the evoked potential. Climbing fibers respond synchronously with the development of the sharp negative deflection of the evoked potentials and were, for the first time, identified. Finally, the Purkinje cell axons exhibited the same firing pattern as the Purkinje cells. Cutaneous and visceral afferents use not only common elements of the cerebellar cortex but also common pathways, in spite of measurable differences between both afferents.
References
Armstrong, D. M., Eccles, J. C., Harvey, R. J., Matthews, P. B. C.: Responses in the dorsal accessory olive of the cat to stimulation of hind limb afferents. J. Physiol. (Lond.)194, 125–145 (1968).
Bremer, F., Bonnet, V.: Caratères généraux de la réponse du cervelet à une volée d'influx afférents. J. Physiol. (Paris)43, 622–665 (1951).
—, Gernandt, B. E.: A micro-electrode analysis of the acoustic response and the strychnin convulsive patterns of the cerebellum. Acta physiol. scand.30, 120–136 (1953).
Carrea, R. M. E., Grundfest, H.: Electrophysiological studies of cerebellar inflow. I. Origin, conduction and termination of ventral spino-cerebellar tract in monkey and cat. J. Neurophysiol.17, 208–238 (1954).
Combs, C. M.: Electro-anatomical study of cerebellar localization, stimulation of various afferents. J. Neurophysiol.17, 123–143 (1954).
Dow, R. S., Anderson, R.: Cerebellar action potentials in response to stimulation of proprioceptors and exteroceptors in the rat. J. Neurophysiol.5, 363–371 (1942).
Eccles, J. C., Llinás, R., Sasaki, K.: Excitation of cerebellar Purkinje cells by the climbing fibres. Nature (Lond.)203, 245–246 (1964).
———: The excitatory synaptic action of climbing fibers on the Purkinje cells of the cerebellum. J. Physiol. (Lond.)182, 268–296 (1966).
Eccles, J. C., Provini, L., Strata, P., Táboříková, H.: Analysis of electrical potentials evoked in the cerebellar anterior lobe by stimulation of hindlimb and forelimb nerves. Exp. Brain Res.6, 171–194 (1968).
Granit, R., Phillips, C. G.: Excitatory and inhibitory processes acting upon individual Purkinje cells of the cerebellum in cats. J. Physiol. (Lond.)133, 520–547 (1956).
——: Effects on Purkinje cells of surface stimulation of the cerebellum. J. Physiol. (Lond.)135, 73–92 (1957).
Grundfest, H., Campbell, B.: Origin, conduction and termination of impulses in the dorsal spinocerebellar tract of cats. J. Neurophysiol.5, 275–294 (1942).
Jansen, J., Jr.: Afferent impulses to the cerebellar hemisphere from the cerebral cortex and certain subcortical nuclei. Acta physiol. scand.41, (Suppl. 143), 1–99 (1957).
—, Fangel, Ch.: Observations on cerebrocerebellar evoked potential in the cat. Exp. Neurol.3, 160–173 (1961).
Laporte, Y., Lundberg, A., Oscarsson, O.: Functional organization of the dorsal spino-cerebellar tract in the cat. II. Single fibre recording in Flechsig's fasciculus on electrical stimulation of various peripheral nerves. Acta physiol. scand.36, 188–203 (1956).
Morin, F., Catalano, J. V., Lamarche, G.: Wave form of cerebellar evoked potentials. Amer. J. Physiol.188, 263–273 (1957).
Mountcastle, V. B., Covian, M. R., Harrison, C. R.: The central representation of some forms of deep sensibility. Res. Publ. Ass. nerv. ment. Dis.30, 399–370 (1952).
Rubia, F. J.: The effects of decerebration on the potentials evoked in the cerebellar cortex by activation of visceral afferents. (In preparation.)
-Rubia, F. J., Nacimiento, A. C.: The projection of visceral afferents to the cerebellar cortex. (In preparation.)
Scheibel, M. E., Scheibel, A. B.: Observations on intracortical relations of the climbing fibers of the cerebellum. A Golgi study. J. comp. Neurol.101, 733–763 (1954).
Sedgwick, E. M., Williams, T. D.: Afferent connections to single units in the inferior olive of the cat. Nature (Lond.)212, 1370–1371 (1966).
Snider, R. S., Stowell, A.: Receiving areas of the tactile, auditory, and visual systems in the cerebellum. J. Neurophysiol.7, 331–357 (1944).
Suda, I., Amano, T.: An analysis of evoked cerebellar activity. Arch. ital. Biol.102, 156–182 (1964).
Szentágothai, J., Rajkovits, K.: Über den Ursprung der Kletterfasern des Kleinhirns. Z. Anat. Entwickl.-Gesch.121, 130–141 (1959).
Talbott, R. E., Towe, A. L., Kennedy, T. T.: Physiological and histological classification of cerebellar neurons in chloralose-anaesthetized cats. Exp. Neurol.19, 46–64 (1967).
Thach, W. T., Jr.: Somatosensory receptive fields of single units in cat cerebellar cortex. J. Neurophysiol.30, 675–696 (1967).
Widén, L.: Cerebellar representation of high threshold afferents in the splanchnic nerve. Acta physiol. scand.33, (Suppl. 117) 1–69 (1955).
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Rubia, F.J., Phelps, J.B. Responses of the cerebellar cortex to cutaneous and visceral afferents. Pflugers Arch. 314, 68–85 (1970). https://doi.org/10.1007/BF00587047
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DOI: https://doi.org/10.1007/BF00587047