Abstract
Production of proteolytic enzyme in a bubble column bioreactor was carried out using the microorganism Rhizopus oryzae. Optimization of the production conditions were done adopting the EVOP (evolutionary operation technique). Studies on two variable and three variable parameters were carried out. The variable parameters were air flow rate, aeration time and incubation period. 8 hours aeration time per day, 1.66 vvm air flow rate and 2 days incubation was found to be optimum.
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Prasad, S., Banerjee, R. & Bhattacharyya, B.C. Production of proteolytic enzyme by Rhizopus oryzae in a bubble column bioreactor. Bioprocess Engineering 13, 41–43 (1995). https://doi.org/10.1007/BF00368764
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DOI: https://doi.org/10.1007/BF00368764